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. 2024 Oct 5;16(10):e70912. doi: 10.7759/cureus.70912

Figure 3. Relative mRNA expression of COX-2 in LPS-stimulated RAW264.7 cells.

Figure 3

The bar chart presents the median and interquartile range (IQR) of relative mRNA expression levels of COX-2 across different treatment groups. Each column represents a distinct treatment group, with the median values indicated by the height of the bars and the IQR depicted by the error bars. Below each column, two rows detail the specific concentrations administered to each group. The dash (“-”) denotes that the respective treatment group did not receive the specified treatment.

(A) Relative mRNA expression of COX-2 in groups treated with phenelzine, two concentrations of serotonin, and their combination, compared to a 0.85% water control. (B) Relative mRNA expression of COX-2 in groups treated with 5-HIAA and its combination with phenelzine, compared to a 0.03% DMSO control.

*p < 0.05; **p < 0.01; ***p < 0.001.

LPS: Lipopolysaccharide; DMSO: Dimethyl sulfoxide; 5-HIAA: 5-Hydroxyindole acetic acid.