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. 2024 Oct 5;16(10):e70912. doi: 10.7759/cureus.70912

Figure 5. Cytokine production in LPS-stimulated RAW264.7 cells measured by ELISA.

Figure 5

The bar chart presents the median and interquartile range (IQR) of cytokine production across different treatment groups in picograms per milliliter. Each column represents a distinct treatment group, with the median values indicated by the height of the bars and the IQR depicted by the error bars. Below each column, two rows detail the specific concentrations administered to each group. The dash (“-”) denotes that the respective treatment group did not receive the specified treatment.

(A, C, and E) Production of IL-6, TNF-α, and IL-10 in groups treated with phenelzine, two concentrations of serotonin, and their combination, compared to a 0.85% water control. (B, D, and F) Production of IL-6, TNF-α, and IL-10 in groups treated with 5-HIAA and its combination with phenelzine, compared to a 0.03% DMSO control.

*p < 0.05; **p < 0.01; ***p < 0.001.

LPS: Lipopolysaccharide; DMSO: Dimethyl sulfoxide; 5-HIAA: 5-Hydroxyindole acetic acid; ELISA: Enzyme-linked immunosorbent assays.