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. 2024 Sep 5;10(20):e37505. doi: 10.1016/j.heliyon.2024.e37505

Table 4.

IC50 (μM) and SI values obtained for the PC-3, SNB-19, and RAW-264.7 cell lines treated with [Cu(Gln)(phen)(H2O)]NO3·H2O complex for 72 h.


Cell line
Histotype aIC50 μM (CI 95 %)/SI
[Cu(Gln)(phen)(H2O)]NO3·H2O Cisplatin
PC3 Prostate 3.3 (2.6–4.1)/1.3 4.8 (3.3–7.0)
SNB19 Glioblastoma 3.8 (3.3–4.6)/1.1 2.9 (2.3–3.6)
RAW 264.7 Macrophage 4.2 (3.8–4.6)

CI 95 %: Data are presented as IC50 values and 95 % confidence interval.

S.I.: Selectivity index - IC50 value in the non-tumor cell line (RAW 264.7) divided by the IC50 value in the tumor cell lines.

a

IC50: Half-maximal inhibitory concentration.