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. 2024 Nov 4;15:9517. doi: 10.1038/s41467-024-53689-1

Fig. 4. Association between polygenic risk score (PRS) of WMH and insular thickness-derived PC1 and the risk of each vascular dementia, all-cause dementia, and late-onset Alzheimer’s disease.

Fig. 4

The odds ratios were calculated in FinnGen (consisting of a total of 500, 348 individuals) by comparing each of the top nine PRS deciles to the lowest decile and adjusting for age, sex, the first 10 genetic principal components and genotyping arrays. Error bars represent 95% confidence intervals. The exact p-values are available in the Source Data.