Table 2. Number of adverse events (n=15).

Adverse events	G1, n	G2, n	G3, n	G4, n	Total, n (%)	≥ G3, n (%)
Hematological
Anemia	9	1	0	0	10 (66.7)	0
Neutropenia	0	0	2	4	6 (40.0)	6 (40.0)
Febrile neutropenia	0	0	3	0	3 (20.0)	3 (20.0)
Leukopenia	0	0	2	3	5 (33.3)	5 (33.3)
Thrombocytopenia	3	0	0	0	3 (20.0)	0
Non-hematological
Edema of the limbs	2	2	1	0	5 (33.3)	1 (6.7)
Anorexia	3	2	0	0	5 (33.3)	0
Malaise	4	1	0	0	5 (33.3)	0
Hiccups	3	0	0	0	3 (20.0)	0
Eruption	2	1	0	0	3 (20.0)	0
Pneumonitis	0	1	2	0	3 (20.0)	2 (13.3)
Fatigue	3	0	0	0	3 (20.0)	0
Constipation	1	1	0	0	2 (13.3)	0
Dyspnea	2	0	0	0	2 (13.3)	0
Watering eyes	2	0	0	0	2 (13.3)	0
Insomnia	2	0	0	0	2 (13.3)	0
Paronychia	1	1	0	0	2 (13.3)	0
Oral hemorrhage	2	0	0	0	2 (13.3)	0
Mucositis oral	1	1	0	0	2 (13.3)	0
Nausea	1	0	0	0	1 (6.7)	0
Dehydration	1	0	0	0	1 (6.7)	0
Oral pain	1	0	0	0	1 (6.7)	0
ALT increased	1	0	0	0	1 (6.7)	0
AST increased	1	0	0	0	1 (6.7)	0
Hyponatremia	1	0	0	0	1 (6.7)	0
Creatinine increased	1	0	0	0	1 (6.7)	0
Sinus tachycardia	1	0	0	0	1 (6.7)	0
Hoarseness	1	0	0	0	1 (6.7)	0
Herpes infection	0	1	0	0	1 (6.7)	0
Lung infection	0	0	1	0	1 (6.7)	1 (6.7)
Perianal abscesses	0	1	0	0	1 (6.7)	0
Epistaxis	1	0	0	0	1 (6.7)	0
Bronchopulmonary hemorrhage	1	0	0	0	1 (6.7)	0

G, grade (grading by Common Terminology Criteria for Adverse Events, version 4); ALT, aspartate aminotransferase; AST, alanine aminotransferase.