表 2. Multivariate logistic regression analysis of the correlation between MSH2, MSH6, and villin expression and clinical pathological parameters of colon cancer.
多因素logistic回归分析癌组织中MSH2、MSH6、villin表达与结肠癌临床病理参数的相关性
| Variable | β | SE | Wald χ2 | OR | 95% CI | P |
| β: partial regression coefficient; SE: standard error; OR: odds ratio; CI: confidence interval. | ||||||
| Negative expression of MSH2 | ||||||
| Age≤60 yr. | 1.020 | 0.487 | 4.387 | 2.773 | 1.068-7.203 | 0.037 |
| Tumor lesion located in the right colon | 1.043 | 0.416 | 6.286 | 2.838 | 1.256-6.413 | 0.013 |
| Moderate to low differentiation | 1.486 | 0.518 | 8.230 | 4.419 | 1.601-12.198 | 0.004 |
| Lymph node metastasis | 0.893 | 0.341 | 6.858 | 2.442 | 1.252-4.765 | 0.009 |
| Negative expression of MSH6 | ||||||
| Age≤60 yr. | 0.935 | 0.406 | 5.304 | 2.547 | 1.149-5.645 | 0.022 |
| Tumor lesion located in the right colon | 0.933 | 0.379 | 6.060 | 2.542 | 1.209-5.343 | 0.014 |
| Moderate to low differentiation | 1.563 | 0.475 | 10.828 | 4.773 | 1.881-12.110 | 0.001 |
| Lymph node metastasis | 0.542 | 0.246 | 4.854 | 1.719 | 1.062-2.785 | 0.028 |
| Negative expression of villin | ||||||
| Infiltration depth is between T3-T4 | 0.667 | 0.285 | 5.477 | 1.948 | 1.114-3.406 | 0.019 |
| Lymph node metastasis | 0.641 | 0.234 | 7.504 | 1.898 | 1.200-3.003 | 0.006 |
| Transfer appears in the distance | 0.415 | 0.168 | 6.102 | 1.514 | 1.090-2.105 | 0.014 |
| Clinical stages Ⅱ-Ⅲ | 1.739 | 0.543 | 10.257 | 5.692 | 1.963-16.499 | 0.001 |