表 3. Resistance and susceptibility rates of 1152 Escherichia coli isolates to antimicrobial agents in 2019 to 2023.
2019−2023年1152株大肠埃希菌对抗菌药物的耐药率和敏感率
| Antimicrobial agents | 2019 | 2020 | 2021 | 2022 | 2023 | χ2/P | |||||||||
| R/% | S/% | R/% | S/% | R/% | S/% | R/% | S/% | R/% | S/% | ||||||
| R: resistant; S: susceptible. | |||||||||||||||
| Amikacin | 2.5 | 97.5 | 1.6 | 98.4 | 3.4 | 96.6 | 2.2 | 97.8 | 0.9 | 99.1 | 3.454/0.485 | ||||
| Gentamicin | 34.5 | 63.5 | 42.9 | 56.6 | 32.9 | 66.7 | 29.8 | 69.8 | 34.7 | 65.3 | 15.144/0.056 | ||||
| Imipenem | 2.5 | 97.5 | 2.2 | 97.8 | 3.4 | 96.6 | 2.2 | 97.8 | 1.4 | 98.6 | 1.951/0.745 | ||||
| Meropenem | 2.5 | 97.5 | 2.2 | 97.8 | 3.4 | 96.6 | 2.2 | 97.3 | 1.4 | 98.6 | 5.466/0.707 | ||||
| Ertapenem | 2.5 | 97.5 | 2.2 | 97.8 | 3.9 | 96.1 | 2.7 | 97.3 | 1.4 | 98.6 | 2.703/0.609 | ||||
| Cefazolin | 55.5 | 44.5 | 57.1 | 42.9 | 54.5 | 45.5 | 61.6 | 38.4 | 79.1 | 20.9 | 30.984/0.000 | ||||
| Cefuroxime | 55.0 | 40.0 | 57.5 | 38.7 | 51.2 | 43.4 | 52.0 | 42.7 | 60.7 | 36.9 | 7.137/0.522 | ||||
| Ceftazidime | 28.5 | 69.0 | 22.1 | 76.8 | 22.7 | 76.3 | 21.8 | 77.3 | 27.6 | 69.7 | 9.133/0.331 | ||||
| Cefotaxime | 51.0 | 47.6 | 55.2 | 43.6 | 51.2 | 48.8 | 49.3 | 49.8 | 57.7 | 41.8 | 6.991/0.538 | ||||
| Cefepime | 27.0 | 71.5 | 26.8 | 72.0 | 26.5 | 72.5 | 28.0 | 70.1 | 33.6 | 63.7 | 15.736/0.046 | ||||
| Piperacillin | 79.0 | 18.0 | 82.3 | 17.7 | 83.4 | 16.1 | 79.9 | 19.2 | 84.4 | 15.1 | 13.154/0.107 | ||||
| Ampicillin | 82.5 | 17.0 | 83.5 | 14.8 | 84.5 | 13.5 | 82.2 | 17.8 | 84.9 | 14.2 | 7.478/0.486 | ||||
| Cefoperazone-Sulbactam | 5.6 | 88.3 | 4.4 | 86.8 | 6.2 | 80.7 | 4.8 | 80.1 | 6.9 | 67.4 | 35.933/0.000 | ||||
| Piperacillin-Tazobactam | 17.7 | 81.8 | 11.2 | 86.6 | 18.4 | 79.6 | 10.8 | 86.5 | 12.5 | 84.0 | 13.108/0.108 | ||||
| Ampicillin-Sulbactam | 57.3 | 42.7 | 47.8 | 52.2 | 48.8 | 51.2 | 42.0 | 57.1 | 45.9 | 51.4 | 25.436/0.001 | ||||
| Ciprofloxacin | 61.5 | 24.5 | 65.4 | 29.1 | 65.2 | 29.5 | 60.4 | 32.4 | 69.2 | 28.0 | 25.100/0.001 | ||||
| Levofloxacin | 56.5 | 17.0 | 64.1 | 16.6 | 58.0 | 30.0 | 54.7 | 36.9 | 63.0 | 32.9 | 76.304/0.000 | ||||
| Trimethoprim-Sulfamethoxazole | 48.7 | 51.3 | 58.8 | 41.2 | 57.0 | 43.0 | 47.3 | 52.7 | 53.2 | 46.8 | 8.119/0.087 | ||||
| Nitrofurantoin | 3.2 | 89.8 | 0 | 91.9 | 0 | 91.7 | 1.1 | 97.7 | 0.8 | 96.1 | 14.505/0.070 | ||||