Table 1. Short List of Top E2-Regulated Proteins in the Cytosolic, Nuclear, and Membrane/Organelle Fractions.

	UniProt ID	gene name	SILAC L/H ratio	no peptide	protein name
cytosolic fraction	Q04637	EIF4G1	4.83	2	eukaryotic translation initiation factor 4 gamma 1
	P00918	CA2	3.37	4	carbonic anhydrase 2
	Q3YEC7	RABL6	2.94	2	RAB, member RAS oncogene family like 6
	Q8TD06	AGR3	2.94	3	anterior gradient 3
	P05161	ISG15	0.25	4	ISG15 ubiquitin like modifier
	P61019	RAB2A	0.22	3	RAB2A, member RAS oncogene family
	Q9Y6U3	SCIN	0.09	6	scinderin
nuclear fraction	Q6UXG2	ELAPOR1	3.99	2	endosome-lysosome associated apoptosis and autophagy regulator 1
	P38159	RBMX	3.27	10	RNA binding motif protein X-linked
	Q8TD06	AGR3	3.20	4	anterior gradient 3
	P00918	CA2	3.05	5	carbonic anhydrase 2
	Q16629	SRSF7	0.34	3	serine and arginine rich splicing factor 7
	P05161	ISG15	0.23	2	ISG15 ubiquitin like modifier
membrane/organelle fraction	Q6ZRV2	FAM83H	15.58	18	family with sequence similarity 83 member H
	O95747	OXSR1	12.99	6	oxidative stress responsive kinase 1
	Q6P996	PDXDC1	12.13	8	pyridoxal dependent decarboxylase domain containing 1
	Q15365	PCBP1	10.83	8	poly(rC)-binding protein 1
	Q9Y6U3	SCIN	0.14	7	scinderin
	Q08380	LGALS3BP	0.12	4	galectin 3 binding protein
	P32004	L1CAM	0.05	8	L1 cell adhesion molecule