Table 2.
Distribution of the genetic test results for hereditary thrombophilia between the groups
| Recurrent Pregnancy Loss Negative (n = 588) |
Recurrent Pregnancy Loss Positive (n = 224) |
p | ||
|---|---|---|---|---|
|
MTHFR C677T n (%) |
Normal | 340 (57.8%) | 113 (50.4%) | 0.027* |
| Heterozygous | 211 (35.9%) | 85 (37.9%) | ||
| Homozygous | 37 (6.3%) | 26 (11.6%) | ||
|
MTHFR A1298C n (%) |
Normal | 433 (73.6%) | 158 (70.5%) | 0.484 |
| Heterozygous | 127 (21.6%) | 57 (25.4%) | ||
| Homozygous | 28 (4.8%) | 9 (4.1%) | ||
|
Factor V Leiden G1691A n (%) |
Normal | 480 (81.6%) | 174 (77.7%) | 0.391 |
| Heterozygous | 100 (17.0%) | 45 (20.1%) | ||
| Homozygous | 8 (1.4%) | 5 (2.2%) | ||
|
Factor II prothrombin G20210A n (%) |
Normal | 568 (96.6%) | 212 (94.6) | 0.226 |
| Heterozygous | 20 (3.4) | 12 (5.4) | ||
| Homocysteine (µmol/L) | 8.57 ± 6.24 | 8.83 ± 5.63 | 0.709 | |
MTHFR: methylenetetrahydrofolate reductase
P < 0.05 statistically significant