Table 2.
The comparison of the outcomes between two groups
| SXD group (n = 53) | Placebo group (n = 48) | P value | |
|---|---|---|---|
| Diarrhea | |||
| Yes | 14 (26.42) | 25 (52.08) | 0.0081a |
| No | 39 (73.58) | 23 (47.92) | |
| No. of chemo cycles with diarrhea | |||
| 0 (%) | 39 (73.58) | 23 (47.92) | 0.0278a |
| 1 (%) | 8 (15.09) | 16 (33.33) | |
| 2 (%) | 6 (11.32) | 9 (18.75) | |
| Degree of diarrhea | |||
| 0 (%) | 39 (73.58) | 23 (47.92) | 0.0097b |
| 1 (%) | 8 (15.09) | 11 (22.92) | |
| 2 (%) | 3 (5.66) | 13 (27.08) | |
| 3 (%) | 3 (5.66) | 1 (2.08) | |
| 4 (%) | 0 (0.00) | 0 (0.00) | |
| 5 (%) | 0 (0.00) | 0 (0.00) | |
| Antidiarrheal medication | |||
| Yes (%) | 6 (11.32) | 19 (39.58) | 0.0010a |
| No (%) | 47 (88.68) | 29 (60.42) | |
| First occurrence time of diarrhea (day) | |||
| Mean | 5.29 | 3.48 | 0.1615b |
| Median | 6 | 3 | |
| Duration of diarrhea (day) | |||
| Mean | 7.83 | 11.11 | 0.5909b |
| Median | 7 | 7 | |
| Degree of neutropenia | |||
| 0 (%) | 30 (56.60) | 19 (39.58) | 0.0465b |
| 1 (%) | 11 (20.75) | 10 (20.83) | |
| 2 (%) | 7 (13.21) | 9 (18.75) | |
| 3 (%) | 5 (9.43) | 10 (20.83) | |
| 4 (%) | 0 (0.00) | 0 (0.00) | |
aChi-square test
bWilcoxon rank sum test