Table 5.
The comparison of safety indicators before and after treatment in two groups
Group/indicator | Baseline | Chemo#1 | P value | Chemo#2 | P value |
---|---|---|---|---|---|
SXD group | |||||
ALT(IU/L) | 28.34 ± 23.28 | 28.68 ± 41.93 | 0.431a | 25.55 ± 18.73 | 0.6669a |
AST(IU/L) | 24.55 ± 14.74 | 21.34 ± 9.83 | 0.0133a | 20.91 ± 7.95 | 0.1047a |
Urea(mmol/L) | 4.89 ± 1.63 | 5.49 ± 2.93 | 0.4248a | 5.21 ± 1.99 | 0.3835a |
CR(μmol/L) | 63.73 ± 14.69 | 65.32 ± 17.12 | 0.1252a | 62.58 ± 15.04 | 0.5677a |
D-D(mg/L) | 0.83 ± 0.97 | 0.91 ± 1.08 | 0.0063a | 0.84 ± 1.06 | 0.9945a |
Placebo group | |||||
ALT(IU/L) | 22.95 ± 19.31 | 22.07 ± 20.32 | 0.9227a | 20.30 ± 16.06 | 0.8679a |
AST(IU/L) | 21.66 ± 10.63 | 20.28 ± 9.25 | 0.3717a | 19.69 ± 10.03 | 0.2507a |
Urea(mmol/L) | 10.82 ± 41.95 | 5.30 ± 1.76 | 0.6439a | 5.49 ± 2.74 | 0.4867a |
CR(μmol/L) | 64.32 ± 12.81 | 64.12 ± 14.35 | 0.8639b | 67.24 ± 21.45 | 0.8027a |
D-D(mg/L) | 1.25 ± 1.53 | 1.26 ± 1.42 | 0.8298a | 1.39 ± 3.21 | 0.4952a |
aWilcoxon rank sum test
bt -test