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. 2024 Nov 5;16:27. doi: 10.1186/s41479-024-00144-w

Table 2.

Comparison by univariate and multivariate analysis of deceased and surviving patients

Alive (N = 384) Deceased (N = 53) p-value Multivariate analysis OR (95%IC) p-value
Characteristics
 Age, years, median (Q1;Q3) 64 (55;72) 71 (66;77) < 0.001 1.09 (1.04;1.15), p = 0.001
 Smoking, n (%) 84 (22%) 16 (31%) NS -
 Coronary artery disease, n (%) 36 (9%) 15 (29%) 0.001 -
 Hypertension, n (%) 158 (41%) 31 (60%) 0.013 -
 Chronic kidney disease, n (%) 26 (7%) 13 (25%) < 0.001 -
 Diabete mellitus, n (%) 38 (10%) 10 (19%) 0.048 -
 Chronic pulmonary disease, n (%) 76 (20%) 18 (35%) 0.0165 -
 Charlson score, median (Q1;Q3) 1 (0;2) 2 (1;5) < 0.001 1.23 (1.02;1.48), p = 0.028
ICU admission
 SAPS II, median (Q1;Q3) 31 (21;42) 49 (40;63) < 0.001 -
 SOFA score, median (Q1;Q3) 3 (2;7) 8 (6;10) < 0.001 1.40 (1.19;1.66), p < 0.001
 PaO2/FiO2 ratio, median (Q1;Q3) 150 (110;188) 130 (90;168) 0,039 -
 CRP, mg/L, median (Q1;Q3) 140 (81.2;212.5) 173.4 (121.5;258.4) 0.0337 -
 Lactates, mmol/L, median (Q1;Q3) 1.2 (1;1.6) 1.6 (1.2;2) < 0.001 1.61 (1.15;2.40), p = 0.011
 D-dimer, ng/mL, median (Q1;Q3) 943 (573;1739) 1447 (811;4000) 0.0066 -
 Lymphocytes 109/L, median (Q1;Q3) 0.71 (0.52;0.93) 0.585 (0.4;0.76) 0.0273 -
ICU stay
 MV, n (%) 236 (61%) 46 (87%) < 0.001 -
 Delay admission-MV, days, median (Q1;Q3) 0;1 (0) 0 (0;1) NS -
 Prone position, n (%) 127 (33%) 35 (66%) < 0.001 4.25 (1.62;12.65),.p = 0.005
 Duration of MV, days, median (Q1;Q3) 9 (5;19) 11 (5;26) NS -
 Vasopressorsa, n (%) 29 (8%) 19 (36%) < 0.001 -
 AKI, n (%) 106 (28%) 29 (56%) < 0.001 -
 Dexamethasone, n (%) 322 (84%) 35 (66%) 0.0022 -
 RRT, n (%) 29 (8%) 25 (47%) < 0.001 -
 ICU LOS, days, median (Q1;Q3) 8 (4;14.3) 9 (5;20) NS -

SAPSII simplified acute physiologic score, SOFA sequential organ failure assessment, MV mechanical ventilation, AKI acute kidney injury, VAP ventilated associated pneumonia, CAPA Covid19 associated pulmonary aspergillosis, RRT renal replacement therapy, LOS length of stay, ICU intensive care unit

anorepinephrine > 0.3µg/kg/min