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. 2024 Nov 5;34:18. doi: 10.1186/s12610-024-00234-1

Table 2.

Socio-demographic and clinical characteristics and sperm parameters and seminal plasma visfatin and vaspin levels in relation to DNA integrity

Normal SDFI group [n = 33] Medium SDFI group [n = 29] Abnormal SDFI group [n = 28] P value
Age (years) 39.58 ± 6.18 39.24 ± 7.20 43.24 ± 11.22 0.211
Infertility duration (years) 7.55 ± 5.88 7.07 ± 5.32 7.76 ± 6.38 0.913
Occupation Risky 4(12.1%) 5(17.2%) 6(21.4%) 0.080
non risky 29(87.9%) 24(82.8%) 22(78.6%)
Special habits Smoker 3(9.1%) 4(13.8%) 5(17.9%) 0.107
Non-smoker 30 (90.9%) 25(86.2%) 23(82.1%)
Height (cm) 175.09 ± 7.12 173.69 ± 7.85 174.24 ± 7.95 0.765
Weight (Kg) 87.24 ± 15.94 82.83 ± 13.53 83.29 ± 11.80 0.430
BMI (Kg/m2) 28.39 ± 4.50 27.54 ± 4.64 27.58 ± 4.39 0.720
Varicocele No 15(45.4%) 14(48.3%) 13(46.4%) 0.568
Left 6(18.2%) 4(13.8%) 4(14.3%)
Bilateral 12(36.4%) 11(37.9%) 11(39.3%)
Sperm concentration (106/ ml) 62.65 ± 45.19 54.78 ± 46.75 33.56 ± 29.44 0.042a
TMC count (106) / ml 30.93 ± 19.35 25.49 ± 11.13 10.42 ± 7.06  < 0.001b
TMC count (106)/ ejaculate 146.63 ± 116.47 65.99 ± 42.92 29.37 ± 19.35  < 0.001b
Motility (%) 44.24 ± 15.65 43.21 ± 13.59 21.00 ± 16.50  < 0.001b
Progressive motility (%) 9.27 ± 6.56 5.48 ± 4.42 4.86 ± 3.29 0.023a
Vitality (%) 61.56 ± 12.62 58.17 ± 20.07 50.93 ± 16.21 0.282
Abnormal forms (%) 91.97 ± 4.39 95.10 ± 2.86 95.65 ± 3.18 0.021a
Leukocyte count (106 / ml) 0.28 ± 0.04 0.26 ± 0.02 0.22 ± 0.03 0.548
Seminal plasma vaspin (ng/ml) 0.87 ± 0.39 0.68 ± 0.39 0.51 ± 0.23 0.005a
Seminal plasma visfatin (ng/ml) 22.45 ± 5.59 19.19 ± 10.05 18.96 ± 4.75 0.004c

Values are mean ± SD or frequency (%)

N.B. BMI Body mass index, SDFI Sperm DNA fragmentation index, TMC Total motile count

aGroup I is significantly different from group 3

bGroup III is significantly different from group 1 and group 2

cGroup I is significantly different from group 2 and group 3