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Prediction and validation of EMR2 3D structure. (A) Ramachandran plot of EMR2 predicted structure showing 98.8% residues I allowed region. (B) Superimposition of native EMR2 (cyan) and D67N variant (magenta), RMSD was 6.34Å. (C) ADGRE2 Domains including egf_5 (raspberry color), egfca_6 (1)(marine blue), egfca_6 (2)(sand color), egfca_6 (3) (magenta color), EGF_3, GPS_3 (cyan color ) and 7tmB2 EMR domain (orange color)
