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. 2024 Oct 7;12(11):e01484-24. doi: 10.1128/spectrum.01484-24

Fig 7.

Bar graphs and line plots depict MVs per colony-forming unit (A), size distribution of OMVs (B), and mean size of MVs (C). WT+3',6-diNn depicts increased MVs per cfu compared with ΔmlaA+3',6-diNn. OMV size distributions overlap.

MVs quantification. MVs P. aeruginosa WT and ∆mlaA in the presence and absence of 3’,6-dinonyl neamine (1× MIC, 2 mg/L, 1 h) were analyzed using a nanoparticle tracking analyzer. (A) Number of MVs produced per colony forming unit (CFU). (B) MVs size distribution in nanometers (nm). Figure 6B was used to calculate the mean size of the membrane vesicles, which is shown in (C). Statistical analysis was performed by one-way ANOVA with Tukey’s multiple-comparison test. ****P < 0.0001, **P < 0.01, *P < 0.05; nsp >0.05.