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. 2024 Oct 15;12(11):e01399-24. doi: 10.1128/spectrum.01399-24

Fig 4.

Graph depicts plaque reduction percentage as a function of CP-COV03 concentration. Plaque reduction decreases as CP-COV03 concentration increases, with higher concentrations leading to more significant reductions in plaque formation.

In vitro inhibitory effect of CP-COV03 against SFTSV replication in Vero cells as determined by a plaque reduction assay. After their infection with 100 × TCID50 of SFTSV for 1 h, Vero cells were treated with increasing concentrations of CP-COV03. The percentage of plaque inhibition relative to the control wells (i.e., without the addition of CP-COV03) was determined for each drug concentration on the second day posttreatment with CP-COV03. IC50 was calculated using Sigma Plot (SPSS Inc.) in an Excel add-in ED50V10.