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. 2024 Nov 5;13:RP93795. doi: 10.7554/eLife.93795

Table 2. Parameter variations that double the mean-squared error of the fits.

Error was measured while a single parameter was systematically varied; other parameters were held fixed at the consensus model values.

Parameter Symbol Units Values: optimal [lower, upper]
Primatecone Mousecone Primaterod Mouserod
Opsin decay rate const. σ s1 22 [14, 34] 9.74 [7.3, 13.1] 7.07 [5.8, 8.8] 7.66 [6.1, 9.3]
PDE dark activation rate η s1 2000 [1300, 3300] 761 [494, 1218] 2.53 [2.1, 3.2] 1.62 [1.3, 2.1]
Ca2+ extrusion rate const. β s1 9 [5, 40] 2.64 [1.58, 5.7] N.A. N.A.
Ca2+ GC affinity KGC μM 0.5 [0, 0.6] 0.4 [0.26 0.46] 0.5 [0.44, 0.53] 0.4 [0.32, 0.44]