Table 1.
Characteristics of studies included in this meta-analysis.
| Study, year | Country | Duration | Study design | Sample size | Age | Gender (M/F) | Follow-up (mo) | Prognostic markers | Survival outcome | Cutoff | Survival analysis | NOS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ong 2017 | China | 2009–2013 | R | 133 | median: 51.92 | 71/62 | median: 52 | LMR | OS/DFS | 5.3/3.2 | M | 8 |
| Diao 2018 1 | China | 2006–2016 | R | 138 | NR | 81/57 | median: 48 | SII | OS/DFS | 484.5 | M | 8 |
| Diao 2018 2 | China | 2004–2014 | R | 171 | NR | 90/81 | median: 45 | SII | OS/DFS | 484.5 | M | 8 |
| Eltohami 2018 | China | 2005–2014 | R | 613 | mean: 50.5 | 556/57 | NR | LMR | OS/DFS | 4.85 | U | 6 |
| Furukawa 2019 | Japan | 2001–2015 | R | 103 | median: 63 | 55/48 | NR | LMR | OS | 4.29 | M | 7 |
| Jariod-Ferrer 2019 | Spain | 2011–2014 | R | 215 | median: 67.5 | 145/70 | median: 31 | LMR | OS | 2.6 | M | 8 |
| Watabe 2019 | Japan | 2004–2012 | R | 110 | median: 68 | 61/49 | median: 68 | LMR | OS/DFS | 5 | M | 8 |
| Hasegawa 2020 | Japan | 2001–2013 | R | 433 | mean: 66.3 | 246/187 | mean: 59.1 | LMR | OS | 4.35 | U | 7 |
| Hung 2020 | China | 2005–2012 | R | 993 | median: 51 | 922/71 | median: 105.6 | SII | OS | 810.6 | M | 8 |
| Lee 2020 | Korea | 2005–2018 | R | 291 | median: 63 | 108/183 | mean: 41 | LMR | OS/DFS | 4.65/4.45 | U | 7 |
| Lu 2020 | China | 2012–2017 | R | 120 | median: 55 | 79/41 | median: 37.5 | LMR, SII | OS/DFS | 4.02, 569 | U, M | 8 |
| Mikoshiba 2020 | Japan | 1991–2018 | R | 101 | median: 59 | 63/38 | median: 65 | LMR | OS/DFS | 5.54 | M | 8 |
| Chen 2021 | China | 2010–2017 | R | 651 | NR | 423/228 | median: 31.1 | LMR | OS | 3.18 | M | 7 |
| Ding 2021 | China | 2012–2015 | R | 493 | NR | 261/232 | NR | LMR | OS/DFS | 3.4 | M | 7 |
| Lin 2021 | China | 2008–2019 | R | 169 | median: 57 | 93/76 | median: 50 | LMR | OS | 4.15 | M | 8 |
| Wei 2021 | China | 2008–2019 | R | 172 | median: 69 | 96/76 | NR | LMR, SII | OS | 3.4, 20.4 | U | 6 |
| Wu 2021 | China | 2005–2012 | R | 890 | median: 50.8 | 828/62 | median: 72.7 | LMR | OS | 4.21 | U | 7 |
| Huang 2022 | China | 2011–2020 | R | 592 | mean: 54.2 | 518/74 | median: 100 | SII | OS/DFS | 337.1/348.33 | M | 8 |
| Kubota 2022 | Japan | 2005–2017 | R | 183 | median: 66 | 103/80 | NR | SII | OS/DFS | 569 | U/M | 7 |
DFS = disease-free survival, M = multivariate, NOS = Newcastle-Ottawa Quality Assessment Scale, NR = not reported, OS = overall survival, R = retrospective, U = univariate.