Table 3.

Subgroup analyses of LMR.

Subgroup	No. of studies	HR (95% CI)	P	Heterogeneity		Model
				I2 (%)	Ph
Overall survival
Country
China	8	0.71 (0.63–0.81)	<.001	23.9	0.239	Fixed
Non-China	6	0.56 (0.34–0.92)	.023	65.4	0.013	Random
Sample size
＞200	7	0.75 (0.66–0.85)	<.001	31	0.192	Fixed
<200	7	0.52 (0.40–0.67)	<.001	34.7	0.163	Fixed
Cut-off
＞4.21	7	0.58 (0.43–0.79)	.001	55	0.038	Random
≤4.21	7	0.75 (0.65–0.87)	<.001	28.9	0.208	Fixed
Analysis
Multivariate	8	0.56 (0.45–0.68)	<.001	32.8	0.166	Fixed
Univariate	6	0.77 (0.67–0.88)	<.001	30.9	0.204	Fixed
Disease-free survival
Country
China	4	0.71 (0.62–0.82)	<.001	0	0.869	Fixed
Non-China	3	0.59 (0.43–0.83)	.002	36.4	0.208	Fixed
Sample size
＞200	3	0.68 (0.56–0.82)	<.001	0	0.581	Fixed
<200	4	0.71 (0.59–0.84)	<.001	19.3	0.294	Fixed
Cut-off
＞4.21	4	0.68 (0.56–0.84)	<.001	30	0.232	Fixed
≤4.21	3	0.70 (0.59–0.83)	<.001	0	0.753	Fixed
Analysis
Multivariate	4	0.69 (0.58–0.81)	<.001	27.1	0.249	Fixed
Univariate	3	0.70 (0.57–0.87)	.001	0	0.687	Fixed

HR = hazard ratio, LMR = lymphocyte-to-monocyte ratio.