TABLE 2.
Analytical sensitivities, specificities, and predictive values of IgM detection in relation to PCR resultsa
| Assay | No. (%) of serum specimens
|
PPV (%) | NPV (%) | % Agreement | |
|---|---|---|---|---|---|
| Case sera testing positive (n = 31)b | Control sera testing negative (n = 96) | ||||
| AniLabsystems | 24 (77) | 88 (92) | 24/32 (75) | 88/95 (93) | 88.1 |
| Biotest | 16 (52) | 91 (95) | 16/21 (73) | 91/106 (86) | 84.3 |
| CFT | 20 (65) | 93 (97) | 20/23 (87) | 93/104 (89) | 89.0 |
| Diagnosys | 18 (58) | 90 (94) | 18/24 (75) | 90/103 (87) | 85.0 |
| ImmunoCard | 12 (48)c | 76 (79) | 12/32 (38) | 76/89 (85) | 72.7 |
| ImmunoWell | 11 (35) | 92 (96) | 11/15 (73) | 92/112 (82) | 81.1 |
| Novum | 22 (71) | 47 (49) | 22/71 (31) | 47/56 (84) | 54.3 |
| Platelia | 16 (52) | 94 (98) | 16/18 (89) | 94/109 (86) | 86.6 |
| Ridascreen | 11 (35) | 96 (100) | 11/11 (100) | 96/116 (83) | 84.3 |
| Serion classic | 15 (48) | 91 (95) | 15/20 (75) | 91/107 (86) | 83.5 |
| SeroMP | 22 (71) | 84 (88) | 22/34 (65) | 84/93 (92) | 83.5 |
| SerodiaMycoII | 20 (65) | 84 (88) | 20/32 (63) | 84/95 (88) | 81.9 |
| Virotech | 14 (45) | 92 (96) | 14/18 (78) | 92/109 (84) | 83.5 |
a
Equivocal results were considered negative.
b
More than 6 days after disease onset.
c
n = 25.