Table 2.
AUC, 95% CI, sensitivity and especificity for CG as a screening test for hypogammaglobulinemia.
| Age Group | AUC | 95% CI | P value | Cut-off value (g/L) | Sensitivity | Especificity | Samples | |
|---|---|---|---|---|---|---|---|---|
| Below reference* |
Normal | |||||||
| <1 year | 0.86 | 0.76 - 0.95 | 0.003 | 13.80 | 80.1% | 83.3% | 6 | 141 |
| 1 year to < 4 years | 0.84 | 0.73 - 0.96 | 0.002 | 20.25 | 70.6% | 85.7% | 7 | 296 |
| 4 years to < 10 years | 0.96 | 0.92 - 1.00 | < 0,001 | 19.85 | 95.6% | 87.5% | 8 | 317 |
| 10 years to < 18 years | 0.95 | 0.92 - 0.98 | < 0,001 | 23.10 | 76.3% | 100.0% | 26 | 283 |
| All ages | 0.86 | 0.82 - 0.89 | < 0.001 | 20.25 | 77.0% | 78.7% | 47 | 1037 |
*Number of samples with serum IgG values below reference for each age group.