TABLE 2.
Variables associated with in-hospital mortality (n = 337) for 755 patients with melioidosisa
| Variable | No. of patients | Univariate odds ratio (95% CI) | Multiple-variable odds ratio (95% CI) |
|---|---|---|---|
| Age | 1.02 (1.006, 1.03) | 1.02 (1.01, 1.03) | |
| Diabetes | 363 | 0.41 (0.30, 0.55) | 0.36 (0.25, 0.50) |
| Pneumonia | 362 | 1.7 (1.3, 2.3) | 2.2 (1.6, 3.1) |
| Positive blood culture | 487 | 5.0 (3.6, 7.1) | 5.8 (4.0, 8.5) |
| Prior administration of active antibioticsb | 161 | 0.45 (0.31, 0.65) | 0.58 (0.38, 0.89) |
| Negative urine culture | 584 | 1.0 | 1.0 |
| Positive urine culture | 171 | 2.7 (1.9, 3.9) | 2.0 (1.3, 2.9) |
| Positive spun pellet only (<103 CFU/ ml) | 52 | 2.1 (1.2, 3.8) | 1.3 (0.70, 2.5) |
| Positive (103 to 105 CFU/ml) | 51 | 2.4 (1.3, 4.3) | 1.5 (0.77, 2.9) |
| Positive (>105 CFU/ ml) | 68 | 3.7 (2.1, 6.5) | 3.3 (1.8, 6.1) |
b
Meropenem, imipenem, ceftazidime, or coamoxiclav.
a
Gender and the presence of urinary symptoms were not significantly associated with mortality in a univariate or multiple-variable models.