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. 2024 Oct 23;15:1464858. doi: 10.3389/fimmu.2024.1464858

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Copyright © 2024 Meng, Zhang, Xu, Ding, Yu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Other virulence factors of Salmonella and pyroptosis. SiiD inhibits the expression of caspase-1 in BMDMs by inhibiting the expression of ROS, thereby suppressing the inflammatory response, but it hasn’t yet been proven to inhibit the occurrence of pyroptosis. DinJ can inhibit the expression of the NLRP3 and caspase-1 in BMDMs and J774A.1 macrophages, but further inhibition of pyroptosis remains to be confirmed. GalE can inhibit the expression of the NLRP3 inflammasome and caspase-1 in BMDMs, and whether it can further inhibit pyroptosis remains to be verified.