(B) | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Results of ASQ-3 | Communication | Gross motor | Fine motor | Problem solving | ||||||||
Normal | Borderline or suspect | P-value | Normal | Borderline or suspect | P-value | Normal | Borderline or suspect | P-value | Normal | Borderline or suspect | P-value | |
Clinical and paraclinical data | ||||||||||||
Minimal pre-ductal saturation (%) | 82.1 ± 9.5 | 69.9 ± 14.2 | 0.001 | 79.9 ± 11.3 | 74.7 ± 14.7 | 0.23 | 80.9 ± 10.5 | 70.2 ± 14.7 | 0.008 | 78.9 ± 11.9 | 79.4 ± 13.4 | 0.90 |
Management and evolution data | ||||||||||||
Duration of intensive care stay (days) | 11.2 ± 11.0 | 13.2 ± 16.4 | 0.54 | 11.1 ± 10.6 | 14.5 ± 19.3 | 0.73 | 9.8 ± 7.7 | 20.2 ± 23.5 | 0.14 | 11.0 ± 11.5 | 15.6 ± 17.9 | 0.38 |
Total length of hospital stay (days) | 24.2 ± 18.5 | 26.2 ± 26.4 | 0.71 | 39.1 ± 64.8 | 97.2 ± 132.1 | 0.29 | 21.7 ± 15.2 | 38.1 ± 34.1 | 0.13 | 23.4 ± 19.2 | 32.3 ± 27.9 | 0.57 |
VISc | 35.5 ± 66.0 | 91.0 ± 112.1 | 0.08 | 51.7 ± 70.2 | 161.9 ± 137.1 | 0.09 | 58.3 ± 79.2 | 115.2 ± 128.6 | 0.22 | 59.2 ± 86.7 | 110.9 ± 102.1 | 0.15 |
Dobutamine dosage (N = 22) (µg/kg/min) | 9.4 ± 3.6 | 12.0 ± 3.9 | 0.09 | 9.3 ± 2.5 | 15.0 ± 5.8 | 0.04 | 9.8 ± 3.3 | 12.3 ± 5.2 | 0.32 | 9.4 ± 3.4 | 13.0 ± 4.0 | 0.02 |
Duration of Dobutamine (days) | 1.0 ± 1.6 | 2.8 ± 3.0 | 0.03 | 1.3 ± 1.8 | 2.2 ± 3.3 | 0.65 | 1.2 ± 1.7 | 2.8 ± 3.4 | 0.17 | 1.2 ± 2.0 | 3.1 ± 2.5 | 0.015 |
Total duration of iNOd (days) | 74.1 ± 54.9 | 118.9 ± 112.3 | 0.19 | 12.6 ± 5.4 | 11.8 ± 2.8 | 0.92 | 76.2 ± 56.5 | 127.5 ± 126.2 | 0.30 | 84.2 ± 75.6 | 93.0 ± 77.8 | 0.95 |
Total duration of mechanical ventilation (days) | 163.6 ± 136.1 | 237.4 ± 303.9 | 0.28 | 170.1 ± 129.3 | 254.6 ± 363.2 | 0.81 | 155.7 ± 110.4 | 318.0 ± 369.1 | 0.06 | 180.0 ± 196.9 | 218.9 ± 173.2 | 0.29 |
Total duration of sedation (days) | 5.4 ± 4.5 | 7.6 ± 8.1 | 0.32 | 5.7 ± 4.2 | 8.0 ± 9.8 | 0.91 | 5.0 ± 3.4 | 10.8 ± 9.9 | 0.02 | 5.8 ± 5.5 | 7.6 ± 6.4 | 0.35 |
NB, for quantitative variables with a normal distribution, student test otherwise Wilcoxon (Mann-Whitney). p is significant if p < 0.05.
WGA, weeks of gestational age.
MBP, mean blood pressure.
VIS, vasoactive-inotropic score.
iNO, inhaled nitric oxide.
Bold values indicate significant p-values < 0.05.