Table 1.
Baseline characteristics of study cohort
| Characteristic | Subcategory | Number (percent) Total N = 1420 patients |
|---|---|---|
| Age (year) | ||
| Median | 64 | |
| Range | 18–88 | |
| Age groups | ||
| < 65 year | 738 (52.0) | |
| ≥ 65 year | 682 (48.0) | |
| Sex | ||
| Female | 607 (42.7) | |
| Male | 813 (57.3) | |
| Presenting symptom | ||
| Focal neurological deficits | 599 (42.2) | |
| Headache | 245 (17.3) | |
| Epilepsy | 221 (15.6) | |
| Personality change | 156 (10.9) | |
| Other presenting symptoms | 162 (11.4) | |
| Unknown | 37 (2.6) | |
| Extent of neurosurgery | ||
| Total resection | 575 (40.5) | |
| Subtotal resection | 393 (27.7) | |
| Biopsy | 430 (30.3) | |
| Unknown | 22 (1.5) | |
| Postoperative ECOG performance status | ||
| 0 | 389 (27.4) | |
| 1 | 486 (34.2) | |
| 2 | 246 (17.3) | |
| 3 | 97 (6.8) | |
| 4 | 17 (1.2) | |
| Unknown | 185 (13.0) | |
| IDH-status | ||
| Wildtype | 1115 (78.5) | |
| Mutated | 49 (3.5) | |
| Unknown | 256 (18.0) | |
| MGMT-promoter status | ||
| Methylated | 487 (34.3) | |
| Unmethylated | 504 (35.5) | |
| Unknown | 429 (30.2) | |
| Overall survival (mo) | ||
| Median | 11.6 | |
| Minimum | < 0.1 | |
| Maximum | 70.8 (5.9 years)* | |
*The maximum observation period in this study was 6 years