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. 2024 Nov 5;14:26816. doi: 10.1038/s41598-024-78603-z

Fig. 8.

Fig. 8

Gut microbes mediate the mediating effect and mediating effect ratio of metabolites on acne(two-step method). The causal effect of Bifidobacterium on acne was found to be mediated by DHA and the Degree of Unsaturation. β(EM) and P(EM) represent the beta and P values obtained by MR analysis of exposure and mediator. β(MO) and P(MO) represent the beta and P values obtained by MR analysis of the mediator and outcome. β(EO) represents the beta and P values obtained by MR analysis of the exposure and outcome.