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Gut microbes mediate the mediating effect and mediating effect ratio of metabolites on acne(multivariable MR).
| Exposure | Mediator | Outcome | β1 | β2 | β(EO) | α*(EM) | mediating effect | mediating effect ratio |
|---|---|---|---|---|---|---|---|---|
| g_Bifidobacterium | DHA | Acne | -0.195 | -0.317 | -0.208 | 0.055 | -0.018 | 8.42% |
| g_Bifidobacterium | Degree of Unsaturation | Acne | -0.211 | -0.235 | -0.208 | 0.059 | -0.014 | 6.65% |
