Table 3.
Assessment of anti-SARS-CoV-2 antibodies before and after the booster shots.
| Sobarana Plus (n = 30) |
PastoCovac Plus (n = 37) |
P value | |
|---|---|---|---|
| Anti-Spike IgG | |||
| Before GMT (95% CI) | 45.8 (34.6, 60.7) | 84.1 (50.4, 140.4) | 0.1919§ |
| After GMT (95% CI) | 255.3 (182.8, 356.6) | 363.8 (231.5, 571.9) | 0.4801§ |
| Rise GMT (95% CI) | 186.2 (127.9, 270.9) | 209.7 (130.2, 337.8) | 0.6408§ |
| Fold Rise GMT (95% CI) | 5.6 (3.8, 8.2) | 4.3 (3.2, 5.8) | 0.4569§ |
| Seroconversion, % | 18 (60.0) | 18 (48.7) | 0.354* |
| Seronegative to Seropositive | 1 (3.3) | 1 (2.7) | 0.699** |
| Neutralizing Ab | |||
| Before GMT (95% CI) | 11.6 (7.5, 17.8) | 9.5 (5.4, 16.7) | 0.7622§ |
| After GMT (95% CI) | 33.1 (31.0, 35.4) | 31.7 (28.6, 35.2) | 0.7574§ |
| Rise GMT (95% CI) | 9.0 (5.3, 15.1) | 7.0 (4.1, 12.0) | 0.5202§ |
| Fold Rise GMT (95% CI) | 2.9 (1.9, 4.3) | 3.3 (1.9, 5.7) | 0.6096§ |
| Seroconversion, % | 9 (30.0) | 9 (24.3) | 0.602* |
| Seronegative to Seropositive | 4 (13.3) | 7 (18.9) | 0.742* |
* Pearson Chi-Square; ** Fisher’s Exact Test; § Mann-Withney U.