Figure 1.

Osmotic sweat extraction based wearable glucose monitoring system. A) Optical image of the wearable platform on the fingertip and forearm along with the exploded view schematic. B) Schematic highlighting the interfacing of the platform with the skin and the operating principle of the sweat extraction via osmosis. C) The composition of the potentiometric glucose sensor and how it is interfaced onto the paper channel to measure glucose from the inflowing sweat. D) Sensing mechanism of the self‐powered potentiometric glucose sensor. E) The workflow of sweat glucose detection on body, which involves measuring the sensor baseline, consuming meal, and observing the sweat, blood, and CGM (only diabetic subjects) glucose trends over time. F) Schematic highlighting the synergistic effect added by osmotic forces toward enhanced sweat glucose detection. The acquired raw sensor data is further processed using personalized calibration models in each subject to obtain accurate sweat‐based blood glucose concentration values.