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. 2024 Oct 28;6(4):165–173. doi: 10.36628/ijhf.2024.0048

Table 2. Univariate analysis in the prediction of all-cause death within 5 years.

Variable HR 95% CI p value
Age (per 1 year) 1.053 1.047–1.058 <0.001
Male sex 0.983 0.878–1.100 0.761
BMI (per 1 kg/m2) 0.926 0.911–0.941 <0.001
SBP (per 1 mmHg) 0.999 0.997–1.001 0.444
DBP (per 1 mmHg) 0.992 0.989–0.995 <0.001
Heart rate (per 1/min) 1.001 0.998–1.003 0.601
NYHA functional class IV 1.358 1.212–1.521 <0.001
AF 0.95 0.843–1.070 0.399
Hypertension 1.415 1.252–1.598 <0.001
DM 1.343 1.196–1.507 <0.001
IHD 1.293 1.150–1.454 <0.001
Hemoglobin (per 1 g/dL) 0.855 0.835–0.875 <0.001
Creatinine (per 1 mg/dL) 1.053 1.032–1.076 <0.001
Total cholesterol (per 1 mg/dL) 0.996 0.995–0.998 <0.001
LVEDD (per 1 mm) 0.988 0.982–0.995 <0.001
LVESD (per 1 mm) 0.993 0.988–0.999 0.012
LVEDV (per 1 mL) 0.999 0.998–1.000 0.031
LVESV (per 1 mL) 0.999 0.998–1.000 0.161
LVEF (per 1 %) 0.998 0.995–1.002 0.528
LA diameter (per 1 mm) 1.008 1.002–1.138 0.008
E/E′ ratio (per 1) 1.019 1.014–1.025 <0.001
PASP (per 1mmHg) 1.012 1.009–1.016 <0.001
HF phenotype
HFrEF Reference 0.372
HFmrEF 0.887 0.751–1.048 0.160
HFpEF 0.972 0.856–1.104 0.664
RVGLS (per 1% decrease) 1.019 1.009–1.029 <0.001
RVGLS/PASP ratio (per 1%/mmHg decrease) 2.426 1.821–3.232 <0.001
Use of RAAS-inhibitor at discharge 0.616 0.547–0.694 <0.001
Use of beta-blocker at discharge 0.621 0.554–0.695 <0.001
Use of MRA at discharge 0.844 0.753–0.945 0.003

HR = hazard ratio; CI = confidence interval; BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; NYHA = New York Heart Association; AF = atrial fibrillation; DM = diabetes mellitus; IHD = ischemic heart disease; LVEDD = left ventricular end-diastolic dimension; LVESD = left ventricular end-systolic dimension; LVEDV = left ventricular end-diastolic volume; LVESV = left ventricular end-systolic volume; LVEF = left ventricular ejection fraction; LA = left atrial; HF = heart failure; HFrEF = heart failure with reduced ejection fraction; HFmrEF = heart failure with mildly-reduced ejection fraction; HFpEF = heart failure with preserved ejection fraction; RVGLS = right ventricular global longitudinal strain; PASP = pulmonary arterial systolic pressure; RAAS = renin-angiotensin-aldosterone system; MRA = mineralocorticoid receptor antagonist.