Table 2.
(a) single nucleotide polymorphisms (SNPs); (b) simple sequence of repeats (variable number tandem repeats and insertion/deletions); (c) dinucleotide repeats.
| (a) | |||
|---|---|---|---|
|
| |||
| GENE | POLYMORPHISM | VARIANT ALLELES | RISK ALLELE |
| Dopamine D1 Receptor DRD1 |
rs4532 | A/G | A |
| Dopamine D2 Receptor DRD2 |
rs1800497 | A/G (A1/A2) |
A (A1) |
| Dopamine D3 Receptor DRD3 |
rs6280 | C/T | C |
| Dopamine D4 Receptor DRD4 |
rs1800955 | C/T | C |
| Catechol-O-Methyltransferase COMT |
rs4680 | A/G (Met/Val) |
G (Val) |
| Mu-Opioid Receptor OPRM1 |
rs1799971 | A/G (As/Asp) |
G (Asp) |
| (b) | |||
| GENE | POLYMORPHISM | VARIANT ALLELES | RISK ALLELE |
|
| |||
| Dopamine D4 Receptor DRD4 |
rs761010487 | 48bp repeat 2R - 11R |
≥7R, long form |
| Dopamine Active Transporter DAT1 |
rs28363170 | 40p repeat 3R - 11R |
< 9R |
| Monoamine Oxidase A MAOA |
rs768062321 | 30bp repeat 2R - 5R |
3.5R, 4R, 5R |
| Serotonin Transporter SLC6A4 (5-HTTLPR) |
rs4795541, rs25531 |
43bp repeat, with SNP L/XL and S, G/A |
S, LG |
| (c) | |||
| GENE | POLYMORPHISM | VARIANT ALLELES | RISK ALLELE |
|
| |||
| GABA(A) Receptor, Alpha-3 GABRB3 |
rs764926719 | CA dinucleotide repeat 171 – 201bp sized fragments |
181 |