Table 1.
Baseline characteristics according to the GRIm score.
| Parameters | level | Overall | Low GRIm score | High GRIm score | p |
|---|---|---|---|---|---|
| n | 313 | 81 | 232 | ||
| Age | <51 | 154 (49.2) | 39 (48.1) | 115 (49.6) | 0.927 |
| ≥51 | 159 (50.8) | 42 (51.9) | 117 (50.4) | ||
| Weight | <62 | 149 (47.6) | 37 (45.7) | 112 (48.3) | 0.784 |
| ≥62 | 164 (52.4) | 44 (54.3) | 120 (51.7) | ||
| Height | <1.60 | 105 (33.5) | 22 (27.2) | 83 (35.8) | 0.202 |
| ≥1.60 | 208 (66.5) | 59 (72.8) | 149 (64.2) | ||
| BMI | <23.8 | 156 (49.8) | 37 (45.7) | 119 (51.3) | 0.459 |
| ≥23.8 | 157 (50.2) | 44 (54.3) | 113 (48.7) | ||
| Family history | No | 242 (77.3) | 60 (74.1) | 182 (78.4) | 0.512 |
| Yes | 71 (22.7) | 21 (25.9) | 50 (21.6) | ||
| Basic disease | No | 244 (78.0) | 66 (81.5) | 178 (76.7) | 0.463 |
| Yes | 69 (22.0) | 15 (18.5) | 54 (23.3) | ||
| Hypertension | No | 273 (87.2) | 73 (90.1) | 200 (86.2) | 0.474 |
| Yes | 40 (12.8) | 8 (9.9) | 32 (13.8) | ||
| Diabetes mellitus | No | 297 (94.9) | 77 (95.1) | 220 (94.8) | 1.000 |
| Yes | 16 (5.1) | 4 (4.9) | 12 (5.2) | ||
| Coronary heart disease | No | 300 (95.8) | 77 (95.1) | 223 (96.1) | 0.930 |
| Yes | 13 (4.2) | 4 (4.9) | 9 (3.9) | ||
| Menarche age | <15 | 121 (38.7) | 20 (24.7) | 101 (43.5) | 0.004 |
| ≥15 | 192 (61.3) | 61 (75.3) | 131 (56.5) | ||
| Menopause | No | 152 (48.6) | 33 (40.7) | 119 (51.3) | 0.132 |
| Yes | 161 (51.4) | 48 (59.3) | 113 (48.7) | ||
| Primary tumor site | Upper outer quadrant | 178 (56.9) | 44 (54.3) | 134 (57.8) | 0.359 |
| Lower outer quadrant | 29 (9.3) | 10 (12.3) | 19 (8.2) | ||
| Lower inner quadrant | 23 (7.3) | 3 (3.7) | 20 (8.6) | ||
| Upper inner quadrant | 44 (14.1) | 11 (13.6) | 33 (14.2) | ||
| Central | 39 (12.5) | 13 (16.0) | 26 (11.2) | ||
| Operative time | <75 | 143 (45.7) | 30 (37.0) | 113 (48.7) | 0.092 |
| ≥75 | 170 (54.3) | 51 (63.0) | 119 (51.3) | ||
| Type of surgery | Mastectomy | 293 (93.6) | 74 (91.4) | 219 (94.4) | 0.485 |
| Breast-conserving surgery | 20 (6.4) | 7 (8.6) | 13 (5.6) | ||
| Pathological T Stage | T1 | 167 (53.4) | 45 (55.6) | 122 (52.6) | 0.802 |
| T2 | 134 (42.8) | 33 (40.7) | 101 (43.5) | ||
| T3 | 10 (3.2) | 2 (2.5) | 8 (3.4) | ||
| T4 | 2 (0.6) | 1 (1.2) | 1 (0.4) | ||
| Pathological N Stage | N0 | 129 (41.2) | 38 (46.9) | 91 (39.2) | 0.377 |
| N1 | 97 (31.0) | 26 (32.1) | 71 (30.6) | ||
| N2 | 50 (16.0) | 11 (13.6) | 39 (16.8) | ||
| N3 | 37 (11.8) | 6 (7.4) | 31 (13.4) | ||
| Pathological TNM Stage | I | 85 (27.2) | 25 (30.9) | 60 (25.9) | 0.305 |
| II | 138 (44.1) | 38 (46.9) | 100 (43.1) | ||
| III | 90 (28.8) | 18 (22.2) | 72 (31.0) | ||
| Molecular subtype | Luminal A | 58 (18.5) | 18 (22.2) | 40 (17.2) | 0.712 |
| Luminal B HER2+ | 63 (20.1) | 17 (21.0) | 46 (19.8) | ||
| Luminal B HER2- | 63 (20.1) | 15 (18.5) | 48 (20.7) | ||
| HER2 enriched | 65 (20.8) | 18 (22.2) | 47 (20.3) | ||
| Triple negative | 64 (20.4) | 13 (16.0) | 51 (22.0) | ||
| Chemotherapy | No | 23 (7.3) | 10 (12.3) | 13 (5.6) | 0.079 |
| Yes | 290 (92.7) | 71 (87.7) | 219 (94.4) | ||
| Radiotherapy | No | 220 (70.3) | 53 (65.4) | 167 (72.0) | 0.332 |
| Yes | 93 (29.7) | 28 (34.6) | 65 (28.0) | ||
| Endocrine therapy | No | 150 (47.9) | 35 (43.2) | 115 (49.6) | 0.391 |
| Yes | 163 (52.1) | 46 (56.8) | 117 (50.4) | ||
| Targeted therapy | No | 279 (89.1) | 69 (85.2) | 210 (90.5) | 0.263 |
| Yes | 34 (10.9) | 12 (14.8) | 22 (9.5) |
Abbreviation: GRIm score: Gustave Roussy Immune score; BMI: body mass index.