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. 2024 Oct 14;21(14):2640–2654. doi: 10.7150/ijms.99724

Table 2.

A performance comparison between GRIm score and common hematological parameters.

Parameters level Overall Low GRIm score High GRIm score p
n 313 81 232
ALT <21 142 (45.4) 33 (40.7) 109 (47.0) 0.400
≥21 171 (54.6) 48 (59.3) 123 (53.0)
AST <23 147 (47.0) 36 (44.4) 111 (47.8) 0.690
≥23 166 (53.0) 45 (55.6) 121 (52.2)
AST/ALT <1.44 267 (85.3) 78 (96.3) 189 (81.5) 0.002
≥1.44 46 (14.7) 3 (3.7) 43 (18.5)
LDH <170 156 (49.8) 38 (46.9) 118 (50.9) 0.629
≥170 157 (50.2) 43 (53.1) 114 (49.1)
GGT <14 142 (45.4) 41 (50.6) 101 (43.5) 0.331
≥14 171 (54.6) 40 (49.4) 131 (56.5)
ALB <45 145 (46.3) 43 (53.1) 102 (44.0) 0.198
≥45 168 (53.7) 38 (46.9) 130 (56.0)
TBIL <12.45 156 (49.8) 44 (54.3) 112 (48.3) 0.419
≥12.45 157 (50.2) 37 (45.7) 120 (51.7)
DBIL <3.9 155 (49.5) 47 (58.0) 108 (46.6) 0.099
≥3.9 158 (50.5) 34 (42.0) 124 (53.4)
IBIL <8.29 156 (49.8) 43 (53.1) 113 (48.7) 0.583
≥8.29 157 (50.2) 38 (46.9) 119 (51.3)
TP <74 132 (42.2) 33 (40.7) 99 (42.7) 0.863
≥74 181 (57.8) 48 (59.3) 133 (57.3)
G <29 137 (43.8) 31 (38.3) 106 (45.7) 0.304
≥29 176 (56.2) 50 (61.7) 126 (54.3)
A/G <1.5 104 (33.2) 34 (42.0) 70 (30.2) 0.071
≥1.5 209 (66.8) 47 (58.0) 162 (69.8)
PAB <267 156 (49.8) 36 (44.4) 120 (51.7) 0.318
≥267 157 (50.2) 45 (55.6) 112 (48.3)
CA153 <9.82 156 (49.8) 44 (54.3) 112 (48.3) 0.419
≥9.82 157 (50.2) 37 (45.7) 120 (51.7)
CEA <1.49 156 (49.8) 35 (43.2) 121 (52.2) 0.209
≥1.49 157 (50.2) 46 (56.8) 111 (47.8)
D-D <0.25 151 (48.2) 41 (50.6) 110 (47.4) 0.713
≥0.25 162 (51.8) 40 (49.4) 122 (52.6)
FBG <2.6 153 (48.9) 48 (59.3) 105 (45.3) 0.041
≥2.6 160 (51.1) 33 (40.7) 127 (54.7)
INR <0.97 139 (44.4) 43 (53.1) 96 (41.4) 0.090
≥0.97 174 (55.6) 38 (46.9) 136 (58.6)
White blood cell <5.45 156 (49.8) 53 (65.4) 103 (44.4) 0.002
≥5.45 157 (50.2) 28 (34.6) 129 (55.6)
Neutrophil <3.23 155 (49.5) 68 (84.0) 87 (37.5) <0.001
≥3.23 158 (50.5) 13 (16.0) 145 (62.5)
Lymphocyte <1.70 154 (49.2) 19 (23.5) 135 (58.2) <0.001
≥1.70 159 (50.8) 62 (76.5) 97 (41.8)
NLR Low 105 (33.5) 80 (98.8) 25 (10.8) <0.001
High 208 (66.5) 1 (1.2) 207 (89.2)
Monocyte <0.35 151 (48.2) 48 (59.3) 103 (44.4) 0.030
≥0.35 162 (51.8) 33 (40.7) 129 (55.6)
Platelet <233 153 (48.9) 37 (45.7) 116 (50.0) 0.589
≥233 160 (51.1) 44 (54.3) 116 (50.0)

Abbreviation: GRIm score: Gustave Roussy Immune score; ALT: alanine aminotransferase; AST: aspartate aminotransferase; LDH: lactate dehydrogenase; GGT: γ-glutamyl transpeptidase; ALB: albumin; TBIL: total bilirubin; DBIL: direct bilirubin; IBIL: indirect bilirubin; TP: total protein; G: globularproteins; PAB: prealbumin; CA153: cancer antigen 153; CEA: carcinoembryonic antigen; D-D: D-Dimer; FBG: fibrinogen; INR: international normalized ratio; NLR: neutrophil to lymphocyte ratio.