Table 3.
Parameters | level | Overall | Low GRIm score | High GRIm score | p |
---|---|---|---|---|---|
n | 313 | 81 | 232 | ||
Tumor size | ≤2 | 154 (49.2) | 43 (53.1) | 111 (47.8) | 0.420 |
>2 and<5 | 149 (47.6) | 37 (45.7) | 112 (48.3) | ||
≥5 | 10 (3.2) | 1 (1.2) | 9 (3.9) | ||
Total lymph nodes (TLN) | <16 | 149 (47.6) | 40 (49.4) | 109 (47.0) | 0.808 |
≥16 | 164 (52.4) | 41 (50.6) | 123 (53.0) | ||
Positive lymph nodes (PLN) | <1 | 134 (42.8) | 39 (48.1) | 95 (40.9) | 0.319 |
≥1 | 179 (57.2) | 42 (51.9) | 137 (59.1) | ||
Total axillary lymph nodes (TALN) | <14 | 149 (47.6) | 42 (51.9) | 107 (46.1) | 0.447 |
≥14 | 164 (52.4) | 39 (48.1) | 125 (53.9) | ||
Positive axillary lymph nodes (PALN) | <1 | 157 (50.2) | 49 (60.5) | 108 (46.6) | 0.042 |
≥1 | 156 (49.8) | 32 (39.5) | 124 (53.4) | ||
ER | 0-25% | 144 (46.0) | 36 (44.4) | 108 (46.6) | 0.918 |
26-50% | 26 (8.3) | 6 (7.4) | 20 (8.6) | ||
51-75% | 48 (15.3) | 12 (14.8) | 36 (15.5) | ||
76-100% | 95 (30.4) | 27 (33.3) | 68 (29.3) | ||
PR | 0-25% | 192 (61.3) | 51 (63.0) | 141 (60.8) | 0.709 |
26-50% | 35 (11.2) | 7 (8.6) | 28 (12.1) | ||
51-75% | 35 (11.2) | 11 (13.6) | 24 (10.3) | ||
76-100% | 51 (16.3) | 12 (14.8) | 39 (16.8) | ||
HER2 | Negative | 185 (59.1) | 46 (56.8) | 139 (59.9) | 0.718 |
Positive | 128 (40.9) | 35 (43.2) | 93 (40.1) | ||
Ki67 | 0-25% | 147 (47.0) | 42 (51.9) | 105 (45.3) | 0.568 |
26-50% | 105 (33.5) | 25 (30.9) | 80 (34.5) | ||
51-75% | 46 (14.7) | 12 (14.8) | 34 (14.7) | ||
76-100% | 15 (4.8) | 2 (2.5) | 13 (5.6) | ||
CK5/6 | Negative | 221 (70.6) | 57 (70.4) | 164 (70.7) | 1.000 |
Positive | 92 (29.4) | 24 (29.6) | 68 (29.3) | ||
E-cad | Negative | 11 (3.5) | 5 (6.2) | 6 (2.6) | 0.247 |
Positive | 302 (96.5) | 76 (93.8) | 226 (97.4) | ||
P120 | Negative | 293 (93.6) | 76 (93.8) | 217 (93.5) | 1.000 |
Positive | 20 (6.4) | 5 (6.2) | 15 (6.5) | ||
P53 | Negative | 170 (54.3) | 43 (53.1) | 127 (54.7) | 0.898 |
Positive | 143 (45.7) | 38 (46.9) | 105 (45.3) | ||
Blood vessel invasion | No | 289 (92.3) | 76 (93.8) | 213 (91.8) | 0.730 |
Yes | 24 (7.7) | 5 (6.2) | 19 (8.2) |
Abbreviation: GRIm score: Gustave Roussy Immune score; ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2; E-cad: E-cadherin.