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. 2024 Oct 14;21(14):2640–2654. doi: 10.7150/ijms.99724

Table 3.

A performance comparison between GRIm score and pathological features.

Parameters level Overall Low GRIm score High GRIm score p
n 313 81 232
Tumor size ≤2 154 (49.2) 43 (53.1) 111 (47.8) 0.420
>2 and<5 149 (47.6) 37 (45.7) 112 (48.3)
≥5 10 (3.2) 1 (1.2) 9 (3.9)
Total lymph nodes (TLN) <16 149 (47.6) 40 (49.4) 109 (47.0) 0.808
≥16 164 (52.4) 41 (50.6) 123 (53.0)
Positive lymph nodes (PLN) <1 134 (42.8) 39 (48.1) 95 (40.9) 0.319
≥1 179 (57.2) 42 (51.9) 137 (59.1)
Total axillary lymph nodes (TALN) <14 149 (47.6) 42 (51.9) 107 (46.1) 0.447
≥14 164 (52.4) 39 (48.1) 125 (53.9)
Positive axillary lymph nodes (PALN) <1 157 (50.2) 49 (60.5) 108 (46.6) 0.042
≥1 156 (49.8) 32 (39.5) 124 (53.4)
ER 0-25% 144 (46.0) 36 (44.4) 108 (46.6) 0.918
26-50% 26 (8.3) 6 (7.4) 20 (8.6)
51-75% 48 (15.3) 12 (14.8) 36 (15.5)
76-100% 95 (30.4) 27 (33.3) 68 (29.3)
PR 0-25% 192 (61.3) 51 (63.0) 141 (60.8) 0.709
26-50% 35 (11.2) 7 (8.6) 28 (12.1)
51-75% 35 (11.2) 11 (13.6) 24 (10.3)
76-100% 51 (16.3) 12 (14.8) 39 (16.8)
HER2 Negative 185 (59.1) 46 (56.8) 139 (59.9) 0.718
Positive 128 (40.9) 35 (43.2) 93 (40.1)
Ki67 0-25% 147 (47.0) 42 (51.9) 105 (45.3) 0.568
26-50% 105 (33.5) 25 (30.9) 80 (34.5)
51-75% 46 (14.7) 12 (14.8) 34 (14.7)
76-100% 15 (4.8) 2 (2.5) 13 (5.6)
CK5/6 Negative 221 (70.6) 57 (70.4) 164 (70.7) 1.000
Positive 92 (29.4) 24 (29.6) 68 (29.3)
E-cad Negative 11 (3.5) 5 (6.2) 6 (2.6) 0.247
Positive 302 (96.5) 76 (93.8) 226 (97.4)
P120 Negative 293 (93.6) 76 (93.8) 217 (93.5) 1.000
Positive 20 (6.4) 5 (6.2) 15 (6.5)
P53 Negative 170 (54.3) 43 (53.1) 127 (54.7) 0.898
Positive 143 (45.7) 38 (46.9) 105 (45.3)
Blood vessel invasion No 289 (92.3) 76 (93.8) 213 (91.8) 0.730
Yes 24 (7.7) 5 (6.2) 19 (8.2)

Abbreviation: GRIm score: Gustave Roussy Immune score; ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2; E-cad: E-cadherin.