Table 5.

Association between SDF-1/CXCR4 genotypes and Pre-ESRD disease.

Variable	Non-diabetic kidney disease (N=335)	Pre-ESRD (N=80)	AOR (95% CI)	p value
SDF-1 rs1801157
Additive model
GG	175 (52.2%)	39 (48.7%)	1.000 (reference)
GA	139 (41.5%)	37 (46.3%)	1.163 (0.328-4.123)	p=0.815
AA	21 (6.3%)	4 (5.0%)	0.715 (0.193-2.640)	p=0.614
Dominant model
GG	175 (52.2%)	39 (48.7%)	1.000 (reference)
GA+AA	160 (47.8%)	41 (51.3%)	0.964 (0.276-3.364)	p=0.954
SDF-1 rs2297630
Additive model
GG	267 (79.7%)	65 (81.3%)	1.000 (reference)
GA	60 (17.9%)	13 (16.3%)	0.463 (0.054-3.987)	p=0.483
AA	8 (2.4%)	2 (2.5%)	0.540 (0.085-3.428)	p=0.514
Dominant model
GG	267 (79.7%)	65 (81.3%)	1.000 (reference)
GA+AA	68 (20.3%)	15 (18.8%)	0.440 (0.051-3.772)	p=0.454
SDF-1 rs2839693
Additive model
CC	263 (78.5%)	58 (72.5%)	1.000 (reference)
CT	68 (20.3%)	22 (27.5%)	1.324 (0.345-5.083)	p=0.682
TT	4 (1.2%)	0 (0.0%)	---	---
Dominant model
CC	263 (78.5%)	58 (72.5%)	1.000 (reference)
CT+TT	72 (21.5%)	22 (27.5%)	1.311 (0.342-5.024)	p=0.693
SDF-1 rs266085
Additive model
TT	119 (35.5%)	18 (22.5%)	1.000 (reference)
TC	166 (49.6%)	47 (58.8%)	2.106 (1.090-4.069)	p=0.027
CC	50 (14.9%)	15 (18.7%)	2.208 (0.937-5.204)	p=0.070
Dominant model
TT	119 (35.5%)	18 (22.5%)	1.000 (reference)
TC+CC	216 (64.5%)	62 (77.5%)	2.130 (1.130-4.014)	p=0.019
CXCR4 rs2228014
Additive model
CC	257 (76.7%)	63 (78.8%)	1.000 (reference)
CT	70 (20.9%)	16 (20.0%)	1.103 (0.223-5.456)	p=0.905
TT	8 (2.4%)	1 (1.3%)	0.284 (0.029-2.786)	p=0.280
Dominant model
CC	257 (76.7%)	63 (78.8%)	1.000 (reference)
CT+TT	78 (23.3%)	17 (21.3%)	0.875 (0.184-4.165)	p=0.867
CXCR4 rs6430612
Additive model
CC	310 (92.5%)	77 (96.3%)	1.000 (reference)
CT	25 (7.5%)	3 (3.7%)	1.462 (0.132-16.189)	p=0.757
TT	0 (0.0%)	0 (0.0%)	---	---
Dominant model
CC	310 (92.5%)	77 (96.3%)	1.000 (reference)
CT+TT	25 (7.5%)	3 (3.7%)	1.462 (0.132-16.189)	p=0.757

The adjusted odds ratio (AOR) with their 95% confidence intervals were estimated by multiple logistic regression models.