Figure 4.

Pathways regulated with glycemia in soleus muscle

(A) Plot showing the major KEGG pathways regulated with glycemia in muscle.

(B) Illustration of the mRNAs that comprise selected KEGG terms with the color indication of their Z score value.

(C) Scheme of the insulin signaling pathway, and of the glycolytic, pentose phosphate, and Krebs’ cycle pathways with, in green, the mRNAs whose expression is downregulated with glycemia.

(D) Scheme of the major down and upregulated pathways that are involved in the control of muscle function.