REAGENT or RESOURCE	SOURCE	IDENTIFIER
Critical commercial assays
Insulin RIA/ELISA	Crystal Chem Inc.	Cat#90080
Glucose monitoring system	A. Menarini Diagnostics, France	Glucofix Tech
Deposited data
Transcriptomic data muscle, liver and adipose tissue	Sánchez-Archidona et al.30	GEO: GSE164672
Pancreatic islets transcriptomic data	Sánchez-Archidona et al.30	GEO: GSE140369
Lipidomics data	This paper	https://doi.org/10.5281/zenodo.13827925
Experimental models: Organisms/strains
Mice C57Bl/6, DAB2, Balb/c	Janvier-Labs	Cat#C57BL/6JRj, Cat#DBA/2JRj, Cat#BALB/cJRj
Software and algorithms
MATLAB 9	The MathWorks, Inc.	https://ch.mathworks.com/fr/products/matlab.html
R	R Foundation for Statistical Computing, Vienna, Austria.71	https://www.r-project.org/
STAR-2.5.3a	Dobin. et al.72	https://github.com/alexdobin/STAR
edgeR	Robinson et al.73	https://bioconductor.org/packages/release/bioc/html/edgeR.html
Limma	Ritchie et al.74	https://bioconductor.org/packages/release/bioc/html/limma.html
missForest	Stekhoven et al.75	https://cran.r-project.org/web/packages/missForest/index.html
WGCNA	Langfelder and Horvath31	https://cran.r-project.org/web/packages/WGCNA/index.html
consensusOPLS	Boccard et al.33	https://gitlab.unige.ch/Julien.Boccard/consensusopls
KOPLS-DA	Rantalainen et al.76 and Bylesjo et al.77	https://kopls.sourceforge.net/index.shtml
clusterProfiler	Wu et al.78 and Yu et al.79	https://bioconductor.org/packages/release/bioc/html/clusterProfiler.html
LipidXplorer	Herzog et al.80,81	https://lifs-tools.org/lipidxplorer.html
Other
Regular chow	SAFE (Route De Saint Bris, 89290 AUGY, France)	Cat#SAFEA04
High fat, high sucrose diet	SAFE (Route De Saint Bris, 89290 AUGY, France)	Cat#SAFE235F