Table 2.
Prevalence and distribution of the PfK13 mutations (S522C, A675V, C469Y) and C469Y mutant allele or mixed with wild-type allele across the survey regions
| Region | Valid sequences | Wild Type Only | S522C | A675V | C469Ya | C469Y | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 10–29%b | 30–59%b | 60–89%b | 90–100%c | ||||||||||||||
| n | % | n | % | n | % | N | % | n | % | N | % | n | % | n | % | ||
| Acholi | 59 | 47 | 79.7 | 0 | 0 | 4 | 6.8 | 8 | 13.6 | 5 | 8.5 | 0 | 0.0 | 1 | 1.7 | 2 | 3.4 |
| West Nile | 59 | 58 | 98.3 | 0 | 0 | 0 | 0.0 | 1 | 1.7 | 0 | 0.0 | 1 | 1.7 | 0 | 0.0 | 0 | 0.0 |
| Karamoja | 60 | 41 | 68.3 | 0 | 0 | 5 | 8.3 | 14 | 23.3 | 2 | 3.3 | 1 | 1.7 | 3 | 5.0 | 8 | 13.3 |
| Lango | 60 | 45 | 75.0 | 1 | 1.7 | 5 | 8.3 | 9 | 15.0 | 3 | 5.0 | 5 | 8.3 | 0 | 0.0 | 1 | 1.7 |
| Total | 238 | 191 | 80.3 | 1 | 0.4 | 14 | 5.9 | 32 | 13.4 | 10 | 4.2 | 7 | 2.9 | 4 | 1.7 | 11 | 4.6 |
aIncludes mixed parasite populations with C469Y mutant allele and wild-type alleles
b% mutant in sample
cPrevalence of single clone mutation