Table 2. Survival probability and direct health care costs for patients with incident CKF requiring dialysis according to different definitions.

Definition	Incident cases, n	Survival probability*1, % [95% CI]		Direct health care costs*2 (in €) within 6 months following incident CKF requiring dialysis, rate per person-month [95% CI]*3
		At 3 months	At 6 months	Outpatient	Inpatient	Drugs	Total
a) Gandjour et al., 2020 (10)	190	82.1 [76.8; 87.7]	70.8 [64.4; 77.8]	1864 [1653; 2053]	4067 [3127; 5242]	661 [520; 825]	6797 [5824; 8010]
b) Kolbrink et al., 2023 (3)	178	70.2 [63.8; 77.3]	60.5 [53.4; 68.6]	1906 [1680; 2118]	6556 [4969; 8509]	606 [466; 767]	9606 [8055; 11527]
c) Lonnemann et al., 2017 (13)	213	74.2 [68.5; 80.3]	63.1 [56.7; 70.3]	1554 [1358; 1760]	5503 [4333; 6908]	564 [438; 713]	8020 [6820; 9377]
d) Schellartz et al., 2021 (14)	241	71.8 [66.3; 77.7]	61.4 [55.3; 68.3]	2057 [1847; 2246]	6227 [5019; 7626]	600 [494; 737]	9445 [8267; 10,808]
e) Billing rationale	134	88.1 [82.7; 93.7]	81.3 [74.7; 88.4]	2930 [2762; 3121]	2061 [1582; 2611]	807 [639; 1.012]	6010 [5471; 6632]

*¹ The survival probability was calculated using the Kaplan–Meier method taking censoring into account (31st December or death within an individual year).

*² The direct health care costs from an SHI perspective was determined as all outpatient and inpatient case costs as well as drug costs within 6 months following incident dialysis (index date) with censoring on death or on 31st December of the respective year. All drugs costs with a dispensing date and case costs with a final billing date within the follow-up period were included. Costs were adjusted to the cost level in 2018 according to purchasing power parity (OECD).

*³ The rate per person-month was calculated as the sum of costs divided by the sum of person-time in months in the follow-up period. Bootstrapping with 1000 replications was used to determine 95% confidence intervals.

CKF, chronic renal failure; 95% CI, 95% confidence interval.