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. Author manuscript; available in PMC: 2024 Nov 6.
Published in final edited form as: J Alzheimers Dis. 2024 Oct 3;102(1):89–98. doi: 10.1177/13872877241283692

Table 4.

Multiple regressions (outcome measure Aβ PET status (positive versus negative) for models 2, 3, and 4 including odds ratio (OR), 95% confidence interval (95% CI), and p value for all included model variables.

Variable Model 2 Model 3 Model 4 Model 5
OR 95% CI p OR 95% CI p OR 95% CI p OR 95% CI p
Age 1.07 0.99, 1.15 0.08 1.06 0.98, 1.16 0.15 1.05 0.96, 1.15 0.26 1.06 0.94, 1.19 0.36
Education 1.07 0.91, 1.25 0.42 1.05 0.88, 1.25 0.57 1.04 0.88, 1.25 0.63 1.05 0.81, 1.32 0.81
Gender 1.00 0.44, 2.24 >0.99 0.75 0.30, 1.87 0.53 0.77 0.29, 2.03 0.59 1.84 0.49, 6.96 0.36
APOE ɛ4 7.11 2.60, 19.41 <0.001 7.02 2.37, 20.91 <0.001 7.36 2.37, 22.87 <0.001 14.69 2.45, 88.15 0.004
42/40 0.70 0.41, 1.22 0.21 0.68 0.39, 1.21 0.19 0.48 0.21, 1.09 0.08
ptau-181 2.38 2.38, 3.89 <0.001 2.48 1.49, 4.12 <0.001 3.65 1.83, 7.27 <0.001
CRP 1.00 0.98, 1.02 0.86 1.01 0.97, 1.05 0.78
SAA 1.00 1.00, 1.00 0.73 1.00 0.99, 1.01 0.83
sVCAM1 1.08 0.72, 1.61 0.72 1.34 0.57, 3.11 0.50
TNF α 1.15 0.72, 1.82 0.56 1.41 0.71, 2.80 0.32
TARC 1.00 1.00, 1.00 0.83 1.00 1.00, 1.00 0.31
A2M 1.00 1.00, 1.00 0.54
B2M 1.00 0.99, 1.01 0.77
FVII 1.00 1.00, 1.00 0.03
sICAM1 1.00 1.00, 1.00 0.29
TNC 1.00 1.00, 1.00 0.048
FABP3 1.00 1.00, 1.00 0.042
TPO 1.00 1.00, 1.01 0.15
IL18 1.00 1.00, 1.00 0.57
PPY 1.00 1.00, 1.01 0.03
IL7 1.00 0.93, 1.07 >0.99
I309 0.99 0.95, 1.03 0.50
Eotaxin3 1.00 0.97, 1.03 0.77
IL6 1.40 0.52, 3.82 0.50
IL5 2.80 0.83, 9.50 0.10
IL10 1.41 0.26, 7.76 0.69

FABP3, fatty acid binding protein-3; PPY, pancreatic polypeptide; TARC, thymus and activation related chemokine; TNF, tumor necrosis factor.