Table 4.
Model 2 | Model 3 | Model 4 | Model 5 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | |
Age | 1.07 | 0.99, 1.15 | 0.08 | 1.06 | 0.98, 1.16 | 0.15 | 1.05 | 0.96, 1.15 | 0.26 | 1.06 | 0.94, 1.19 | 0.36 |
Education | 1.07 | 0.91, 1.25 | 0.42 | 1.05 | 0.88, 1.25 | 0.57 | 1.04 | 0.88, 1.25 | 0.63 | 1.05 | 0.81, 1.32 | 0.81 |
Gender | 1.00 | 0.44, 2.24 | >0.99 | 0.75 | 0.30, 1.87 | 0.53 | 0.77 | 0.29, 2.03 | 0.59 | 1.84 | 0.49, 6.96 | 0.36 |
APOE ɛ4 | 7.11 | 2.60, 19.41 | <0.001 | 7.02 | 2.37, 20.91 | <0.001 | 7.36 | 2.37, 22.87 | <0.001 | 14.69 | 2.45, 88.15 | 0.004 |
Aβ42/40 | 0.70 | 0.41, 1.22 | 0.21 | 0.68 | 0.39, 1.21 | 0.19 | 0.48 | 0.21, 1.09 | 0.08 | |||
ptau-181 | 2.38 | 2.38, 3.89 | <0.001 | 2.48 | 1.49, 4.12 | <0.001 | 3.65 | 1.83, 7.27 | <0.001 | |||
CRP | 1.00 | 0.98, 1.02 | 0.86 | 1.01 | 0.97, 1.05 | 0.78 | ||||||
SAA | 1.00 | 1.00, 1.00 | 0.73 | 1.00 | 0.99, 1.01 | 0.83 | ||||||
sVCAM1 | 1.08 | 0.72, 1.61 | 0.72 | 1.34 | 0.57, 3.11 | 0.50 | ||||||
TNF α | 1.15 | 0.72, 1.82 | 0.56 | 1.41 | 0.71, 2.80 | 0.32 | ||||||
TARC | 1.00 | 1.00, 1.00 | 0.83 | 1.00 | 1.00, 1.00 | 0.31 | ||||||
A2M | 1.00 | 1.00, 1.00 | 0.54 | |||||||||
B2M | 1.00 | 0.99, 1.01 | 0.77 | |||||||||
FVII | 1.00 | 1.00, 1.00 | 0.03 | |||||||||
sICAM1 | 1.00 | 1.00, 1.00 | 0.29 | |||||||||
TNC | 1.00 | 1.00, 1.00 | 0.048 | |||||||||
FABP3 | 1.00 | 1.00, 1.00 | 0.042 | |||||||||
TPO | 1.00 | 1.00, 1.01 | 0.15 | |||||||||
IL18 | 1.00 | 1.00, 1.00 | 0.57 | |||||||||
PPY | 1.00 | 1.00, 1.01 | 0.03 | |||||||||
IL7 | 1.00 | 0.93, 1.07 | >0.99 | |||||||||
I309 | 0.99 | 0.95, 1.03 | 0.50 | |||||||||
Eotaxin3 | 1.00 | 0.97, 1.03 | 0.77 | |||||||||
IL6 | 1.40 | 0.52, 3.82 | 0.50 | |||||||||
IL5 | 2.80 | 0.83, 9.50 | 0.10 | |||||||||
IL10 | 1.41 | 0.26, 7.76 | 0.69 |
FABP3, fatty acid binding protein-3; PPY, pancreatic polypeptide; TARC, thymus and activation related chemokine; TNF, tumor necrosis factor.