Figure 2. Modeling Disease Duration in Patients With Multiple Sclerosis.

(A) Scatterplot showing the relationship between the actual disease duration values in the test set (N = 878) and the ones predicted by the model. (B) Scatterplot showing the relationship between the disease duration gap and the brain-age gap (obtained with the DeepBrainNet model) in the test set; marginal density plots are also shown, portraying the distribution of the 2 variables. Linear fit lines are shown as solid lines (with corresponding 95% confidence intervals in gray) while dashed lines represent the line of identity (A) and horizontal and vertical zero reference lines (B), respectively. DD = disease duration; MAE = mean absolute error.