Figure 1.

The clinical course of Parkinson’s disease with the adjustment of foslevodopa/foscarbidopa and concomitant antiparkinsonism medications. Clinical course showing the degree of motor symptoms and psychosis, plasma levodopa concentrations (ng/mL), infusion rates of foslevodopa/foscarbidopa (mL/hr), and concomitant medications. Regarding foslevodopa/foscarbidopa, the solid line indicates the standard infusion rate, and the dotted line indicates the lower alternative infusion rate. AMT, amantadine; CD, carbidopa; CSCI, continuous subcutaneous infusion; IST, istradefylline; LD, levodopa; OPC, opicapone; RSG, rasagiline; ZNS, zonisamide.