Central Illustration.

Association Between Predischarge TMPG in Quartiles 1 to 4 and Outcomes After M-TEER

Impact of transmitral mean pressure gradient (TMPG) on the primary composite outcome of all-cause mortality or heart failure hospitalization at 3 years after M-TEER in (A) all patients; (B) primary mitral regurgitation; and (C) secondary mitral regurgitation. Patients with mixed etiology were excluded from the subgroup analyses shown in (B and C) (N = 15). The panels show adjusted survival analyses stratified by quartiles 1 to 3 versus quartile 4. The variables used for multivariable adjustment are shown in Supplemental Tables 1 to 3. M-TEER = mitral transcatheter edge-to-edge repair.