Table 4.

Quality assessment of enrolled studies using QUADAS-2

Study	Risk of bias				Applicability concerns
	Patient selection	Index test	Reference standard	Flow and timing	Patient selection	Index test	Reference standard
Villeneuve, et al. [18]
Gates, et al. [19]
Bott, et al. [20]
Uhlmann, et al. [21]
Frank, et al. [22]
Gold, et al. [23]
Lee, et al. [24]
Utoomprurkporn, et al. [25]
Hopper, et al. [26]
Kim, et al. [27]

low risk; high risk; unclear risk