Figure 5.

Interactional network of m⁶A-circHECA of cashmere goat with its directly and indirectly regulated target proteins along with signaling pathway enrichment. (a) Interactional regulatory network of m⁶A-circHECA of cashmere goat with its potential target proteins. The potential target proteins directly interacting with m⁶A-circHECA are indicated by bigger round balls with binding motifs with each protein being presented in the outer ring. The remaining target proteins that may be indirectly regulated by m⁶A-circHECA were indicated with smaller round balls. (b) Pathway enrichment analysis of the potential target proteins directly and indirectly regulated by m⁶A-circHECA. The enrichment for signaling pathway was carried out using the CluePedia Cytoscape plugin with default settings. the significantly enriched pathways were presented as a chordmap that was generated by an online platform for data analysis and visualization ( https://www.bioinformatics.com.cn, last access: 24 Nov 2023, Tang et al [18]) (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.).