Table 2.
The cumulative incidence of psychiatric adverse events (AEs) following COVID-19 vaccination.
Diseases | Vaccination | Total number | One week | Two weeks | One month | Three months | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
event | I | 95% CI | p | event | I | 95% CI | p | event | I | 95% CI | p | event | I | 95% CI | p | |||
Schizophrenia | No | 308,354 | 5 | 0.16 | 0.02–0.30 | 0.017 | 7 | 0.23 | 0.06–0.40 | 0.018 | 24 | 0.78 | 0.47–1.09 | <0.001 | 61 | 1.98 | 1.48–2.47 | <0.001 |
Yes | 1,718,999 | 6 | 0.03 | 0.01–0.06 | 12 | 0.07 | 0.03–0.11 | 26 | 0.15 | 0.09–0.21 | 88 | 0.51 | 0.40–0.62 | |||||
Depression | No | 308,354 | 26 | 0.84 | 0.52–1.17 | 0.290 | 54 | 1.75 | 1.28–2.22 | 0.097 | 142 | 4.61 | 3.85–5.36 | 0.026 | 439 | 14.24 | 12.91–15.57 | <0.001 |
Yes | 1,718,999 | 184 | 1.07 | 0.92–1.23 | 386 | 2.25 | 2.02–2.47 | 965 | 5.61 | 5.26–5.97 | 3145 | 18.30 | 17.66–18.93 | |||||
Bipolar disorder | No | 308,354 | 2 | 0.06 | 0.00–0.15 | 0.655 | 4 | 0.13 | 0.00–0.26 | 0.517 | 9 | 0.29 | 0.10–0.48 | 0.299 | 43 | 1.39 | 0.98–1.81 | 0.002 |
Yes | 1,718,999 | 8 | 0.05 | 0.01–0.08 | 15 | 0.09 | 0.04–0.13 | 35 | 0.20 | 0.14–0.27 | 136 | 0.79 | 0.66–0.92 | |||||
Anxiety, dissociative, stress-related, somatoform disorders | No | 308,354 | 48 | 1.56 | 1.12–2.00 | 0.014 | 95 | 3.08 | 2.46–3.70 | <0.001 | 208 | 6.75 | 5.83–7.66 | <0.001 | 625 | 20.27 | 18.68–21.86 | <0.001 |
Yes | 1,718,999 | 389 | 2.26 | 2.04–2.49 | 766 | 4.46 | 4.14–4.77 | 1641 | 9.55 | 9.08–10.01 | 4884 | 28.41 | 27.62–29.21 | |||||
Sleep disorders | No | 308,354 | 29 | 0.94 | 0.60–1.28 | <0.001 | 58 | 1.88 | 1.40–2.36 | <0.001 | 132 | 4.28 | 3.55–5.01 | <0.001 | 376 | 12.19 | 10.96–13.43 | <0.001 |
Yes | 1,718,999 | 330 | 1.92 | 1.71–2.13 | 709 | 4.12 | 3.82–4.43 | 1544 | 8.98 | 8.53–9.43 | 4960 | 28.85 | 28.05–29.66 | |||||
Eating disorders | No | 308,354 | 2 | 0.06 | 0.00–0.15 | 0.169 | 2 | 0.06 | 0.00–0.15 | 0.349 | 3 | 0.10 | 0.00–0.21 | 0.735 | 10 | 0.32 | 0.12–0.53 | 0.724 |
Yes | 1,718,999 | 3 | 0.02 | 0.00–0.04 | 6 | 0.03 | 0.01–0.06 | 14 | 0.08 | 0.04–0.12 | 51 | 0.30 | 0.22–0.38 | |||||
Sexual disorders | No | 308,354 | 0 | 0.00 | 0.00–0.00 | 1.000 | 0 | 0.00 | 0.00–0.00 | 0.617 | 0 | 0.00 | 0.00–0.00 | 0.154 | 1 | 0.03 | 0.00–0.10 | 0.007 |
Yes | 1,718,999 | 1 | 0.01 | 0.00–0.02 | 8 | 0.05 | 0.01–0.08 | 16 | 0.09 | 0.05–0.14 | 46 | 0.27 | 0.19–0.34 |
I cumulative incidence, CI confidence interval.