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. 2024 Jun 4;29(11):3635–3643. doi: 10.1038/s41380-024-02627-0

Table 2.

The cumulative incidence of psychiatric adverse events (AEs) following COVID-19 vaccination.

Diseases Vaccination Total number One week Two weeks One month Three months
event I 95% CI p event I 95% CI p event I 95% CI p event I 95% CI p
Schizophrenia No 308,354 5 0.16 0.02–0.30 0.017 7 0.23 0.06–0.40 0.018 24 0.78 0.47–1.09 <0.001 61 1.98 1.48–2.47 <0.001
Yes 1,718,999 6 0.03 0.01–0.06 12 0.07 0.03–0.11 26 0.15 0.09–0.21 88 0.51 0.40–0.62
Depression No 308,354 26 0.84 0.52–1.17 0.290 54 1.75 1.28–2.22 0.097 142 4.61 3.85–5.36 0.026 439 14.24 12.91–15.57 <0.001
Yes 1,718,999 184 1.07 0.92–1.23 386 2.25 2.02–2.47 965 5.61 5.26–5.97 3145 18.30 17.66–18.93
Bipolar disorder No 308,354 2 0.06 0.00–0.15 0.655 4 0.13 0.00–0.26 0.517 9 0.29 0.10–0.48 0.299 43 1.39 0.98–1.81 0.002
Yes 1,718,999 8 0.05 0.01–0.08 15 0.09 0.04–0.13 35 0.20 0.14–0.27 136 0.79 0.66–0.92
Anxiety, dissociative, stress-related, somatoform disorders No 308,354 48 1.56 1.12–2.00 0.014 95 3.08 2.46–3.70 <0.001 208 6.75 5.83–7.66 <0.001 625 20.27 18.68–21.86 <0.001
Yes 1,718,999 389 2.26 2.04–2.49 766 4.46 4.14–4.77 1641 9.55 9.08–10.01 4884 28.41 27.62–29.21
Sleep disorders No 308,354 29 0.94 0.60–1.28 <0.001 58 1.88 1.40–2.36 <0.001 132 4.28 3.55–5.01 <0.001 376 12.19 10.96–13.43 <0.001
Yes 1,718,999 330 1.92 1.71–2.13 709 4.12 3.82–4.43 1544 8.98 8.53–9.43 4960 28.85 28.05–29.66
Eating disorders No 308,354 2 0.06 0.00–0.15 0.169 2 0.06 0.00–0.15 0.349 3 0.10 0.00–0.21 0.735 10 0.32 0.12–0.53 0.724
Yes 1,718,999 3 0.02 0.00–0.04 6 0.03 0.01–0.06 14 0.08 0.04–0.12 51 0.30 0.22–0.38
Sexual disorders No 308,354 0 0.00 0.00–0.00 1.000 0 0.00 0.00–0.00 0.617 0 0.00 0.00–0.00 0.154 1 0.03 0.00–0.10 0.007
Yes 1,718,999 1 0.01 0.00–0.02 8 0.05 0.01–0.08 16 0.09 0.05–0.14 46 0.27 0.19–0.34

I cumulative incidence, CI confidence interval.