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. 2024 Nov 6;148(1):60. doi: 10.1007/s00401-024-02807-w

Fig. 6.

Fig. 6

Immunoelectron microscopy of a Biondi body. Choroid plexuses from case 8 and anti-TMEM106B antibody TMEM239. The cytoplasm of an ependymal cell contains a round body made of osmiophilic and electron-lucent areas that are surrounded by a crescent-shaped bundle of filaments (interpreted as a Biondi body) decorated by gold particles. The round body has the appearance of a secondary lysosome or a residual body. The nucleus of the cell and numerous mitochondria are seen around the inclusion. Scale bar, 1 µm