Table 4. Inhibitory Effects of Part of the Obtained Compounds against DENV-2 NS2B/NS3a.
compounds | screening at 100 μM (%) | IC50 (μM) |
---|---|---|
2a | 48 ± 1 | >100 |
2b | 21 ± 3 | ND |
2c | 18 ± 3 | ND |
2d | 29 ± 1 | ND |
2e | 52 ± 2 | 65.6 ± 11.4 |
2f | 54 ± 3 | 59.3 ± 6.9 |
2g | 28 ± 2 | ND |
2h | 20 ± 1 | ND |
2j | 22 ± 1 | ND |
2k | 28 ± 4 | ND |
ND: not determine.