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. 2024 Oct 24;9(44):44624–44638. doi: 10.1021/acsomega.4c07148

Table 4. Inhibitory Effects of Part of the Obtained Compounds against DENV-2 NS2B/NS3a.

compounds screening at 100 μM (%) IC50 (μM)
2a 48 ± 1 >100
2b 21 ± 3 ND
2c 18 ± 3 ND
2d 29 ± 1 ND
2e 52 ± 2 65.6 ± 11.4
2f 54 ± 3 59.3 ± 6.9
2g 28 ± 2 ND
2h 20 ± 1 ND
2j 22 ± 1 ND
2k 28 ± 4 ND
a

ND: not determine.