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. 2024 Nov 6;14:26910. doi: 10.1038/s41598-024-76129-y

Table 1.

Comparisons of demographic, perioperative and laboratory indicators between SSI and Non-SSI patients in the training and validation set.

Variables Training set Validation set
SSI Non-SSI P-value SSI Non-SSI P-value
(N = 165) (N = 341) (N = 76) (N = 141)
Demographic Indicators
Gender 0.20 1.00
Female 79 (47.88%) 141 (41.35%) 34 (44.74%) 64 (45.39%)
Male 86 (52.12%) 200 (58.65%) 42 (55.26%) 77 (54.61%)
Age 0.001 0.21
<60 years 98 (59.39%) 253 (74.19%) 52 (68.42%) 109 (77.30%)
≥ 60 years 67 (40.61%) 88 (25.81%) 24 (31.58%) 32 (22.70%)
Smoke status 0.72 0.03
Never 107 (64.85%) 214 (62.76%) 41 (53.95%) 99 (70.21%)
Ever/current 58 (35.15%) 127 (37.24%) 35 (46.05%) 42 (29.79%)
Drink status 0.35 0.72
Never 134 (81.21%) 263 (77.13%) 58 (76.32%) 103 (73.05%)
Ever/current 31 (18.79%) 78 (22.87%) 18 (23.68%) 38 (26.95%)
HBP 0.63 0.03
No 109 (66.06%) 234 (68.62%) 47 (61.84%) 108 (76.60%)
Yes 56 (33.94%) 107 (31.38%) 29 (38.16%) 33 (23.40%)
DM 0.001 0.001
No 97 (58.79%) 251 (73.61%) 40 (52.63%) 106 (75.18%)
Yes 68 (41.21%) 90 (26.39%) 36 (47.37%) 35 (24.82%)
BMI <0.001 0.004
<28 kg/m2 51 (30.91%) 185 (54.25%) 25 (32.89%) 77 (54.61%)
≥ 28 kg/m2 114 (69.09%) 156 (45.75%) 51 (67.11%) 64 (45.39%)
Perioperative indicators
MS: 0.96 0.10
No 115 (69.70%) 240 (70.38%) 47 (61.84%) 104 (73.76%)
Yes 50 (30.30%) 101 (29.62%) 29 (38.16%) 37 (26.24%)
Implant 0.15 0.10
No 18 (10.91%) 55 (16.13%) 9 (11.84%) 31 (21.99%)
Yes 147 (89.09%) 286 (83.87%) 67 (88.16%) 110 (78.01%)
OT: 0.03 0.56
< 3 h 78 (47.27%) 197 (57.77%) 47 (61.84%) 80 (56.74%)
≥ 3 h 87 (52.73%) 144 (42.23%) 29 (38.16%) 61 (43.26%)
IBL 0.09 1.00
< 200 ml 144 (87.27%) 315 (92.38%) 68 (89.47%) 127 (90.07%)
≥ 200 ml 21 (12.73%) 26 (7.62%) 8 (10.53%) 14 (9.93%)
PSD <0.001 <0.001
< 300 ml 21 (12.73%) 165 (48.39%) 12 (15.79%) 70 (49.65%)
≥ 300 ml 144 (87.27%) 176 (51.61%) 64 (84.21%) 71 (50.35%)
GS <0.001 0.005
No 12 (7.27%) 84 (24.63%) 4 (5.26%) 29 (20.57%)
Yes 153 (92.73%) 257 (75.37%) 72 (94.74%) 112 (79.43%)
PTAG 0.60 0.37
No 43 (26.06%) 98 (28.74%) 18 (23.68%) 43 (30.50%)
Yes 122 (73.94%) 243 (71.26%) 58 (76.32%) 98 (69.50%)
NPTA 0.009 0.02
No 110 (66.67%) 266 (78.01%) 45 (59.21%) 106 (75.18%)
Yes 55 (33.33%) 75 (21.99%) 31 (40.79%) 35 (24.82%)
Laboratory indicators
PTHB 0.32 0.09
Normal 57 (34.55%) 135 (39.59%) 32 (42.11%) 42 (29.79%)
Abnormal 108 (65.45%) 206 (60.41%) 44 (57.89%) 99 (70.21%)
PTSA 0.004 0.002
Normal 91 (55.15%) 234 (68.62%) 36 (47.37%) 98 (69.50%)
Abnormal 74 (44.85%) 107 (31.38%) 40 (52.63%) 43 (30.50%)
LKF 0.71 0.09
Normal 67 (40.61%) 146 (42.82%) 40 (52.63%) 56 (39.72%)
Abnormal 98 (59.39%) 195 (57.18%) 36 (47.37%) 85 (60.28%)
K+ 0.001 0.65
Normal 43 (26.06%) 141 (41.35%) 27 (35.53%) 56 (39.72%)
Abnormal 122 (73.94%) 200 (58.65%) 49 (64.47%) 85 (60.28%)
Ca+ 0.18 0.37
Normal 96 (58.18%) 221 (64.81%) 43 (56.58%) 90 (63.83%)
Abnormal 69 (41.82%) 120 (35.19%) 33 (43.42%) 51 (36.17%)
TT <0.001 <0.001
Normal 56 (33.94%) 251 (73.61%) 39 (51.32%) 108 (76.60%)
Abnormal 109 (66.06%) 90 (26.39%) 37 (48.68%) 33 (23.40%)

SSI surgical site infection, HBP high blood pressure, DM diabetes mellitus, BMI body mass index, MS multi-stage surgery, OT operation time, IBL intraoperative blood loss, PSD postoperative suction drainagen, GS gelatin sponge, PTAG postoperative anticoagulation, NPTA none-preoperative antibiotic, PTHB postoperative hemoglobin, PTSA postoperative serum albumin, LKF liver and kidney function, TT thrombin time. Categorical variables were presented as number and percentage (n, %). The bold text means that the P value was < 0.05.