Table 2. Results of Cytotoxicity Assaya.
| results
(% cell viability) | ||
|---|---|---|
| OVCAR3 (μM) | MDA-MB-435 (μM) | |
| orfamide N (1) | 10.50 ± 4.17 | 11.06 ± 5.00 |
| orfamide A (2) | 11.44 ± 3.76 | 11.62 ± 3.92 |
| taxol (nM) | 2.129 ± 0.488 | 5.580 ± 1.298 |
a
Cells were plated and treated with taxol, compound 1, or compound 2 for 72 h. Dose-response curves were generated for OVCAR3 and MDA-MD-435. IC50 values were generated from dose-response curves. Each experiment was performed in three biological replicates and data represent triplicate values ± SEM.